Evidence map›Paper›PMID 29861850›Full record

ArticleOncotarget2018

Breast and ovarian cancer penetrance of

LingJiao Zhang, Vivian Y Shin, Xinglei Chai, Alan Zhang, Tsun L Chan, Edmond S Ma, Timothy R Rebbeck, Jinbo Chen, Ava Kwong

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Breast cancer risk associated withCancer pathogenesis and therapy · 2025
    Article
  2. Somatic and germline aberrations in homologous recombination repair genes among Chinese high-risk breast cancer patients by multi-gene next-generation sequencing.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  3. Age-specific breast and ovarian cancer risks associated with germlineThe Lancet regional health. Western Pacific · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

LingJiao Zhang *Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Vivian Y Shin *Department of Surgery, the University of Hong Kong, Hong Kong.
Xinglei ChaiDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Alan ZhangSidwell High School, Bethesda, MD, USA.
Tsun L ChanDepartment of Molecular Pathology, Hong Kong Sanatorium & Hospital, Hong Kong.
Edmond S MaDepartment of Molecular Pathology, Hong Kong Sanatorium & Hospital, Hong Kong.
Timothy R RebbeckDana Farber Cancer Institute and Harvard TH Chan School of Public Health, Boston, MA, USA.
Jinbo ChenDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Ava KwongDepartment of Surgery, the University of Hong Kong, Hong Kong.
Hong Kong Sanatorium and Hospital · HKUniversity of Pennsylvania · USDana-Farber Cancer Institute · USSidwell Friends School · USUniversity of Hong Kong · HK

Funding

UNIVERSITY OF PENNSYLVANIA CAN CTR SUPPORT GRANTP30CA016520 · NCI · UNIVERSITY OF PENNSYLVANIA · PI SHELLEY L BERGER · 1985 to 2026
$222.3M
Prophytactic surgery in carriers of BRCA 1/2 mutationsR01CA083855 · NCI · UNIVERSITY OF PENNSYLVANIA · PI REBBECK, TIMOTHY R · 2000 to 2010
$7.3M
Modifiers of Cancer Risk in BRCA 1/2 Mutation CarriersR01CA102776 · NCI · UNIVERSITY OF PENNSYLVANIA · PI REBBECK, TIMOTHY R · 2004 to 2008
$3.0M
Statistical Methods for Cancer Absolute Risk PredictionR01CA164305 · NCI · UNIVERSITY OF PENNSYLVANIA · PI CHEN, JINBO · 2013 to 2016
$1.4M
NCI NIH HHS P30 CA016520NCI NIH HHS R01 CA083855NCI NIH HHS R01 CA102776NCI NIH HHS R01 CA164305
6 · The paper itself

Abstract

Germline mutations in

Indexed as

BRCA1BRCA2breast and ovarian cancerChinese populationpenetrance

Identifiers

PMID29861850
PMCPMC5982775
OpenAlexW2792068459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.