Evidence map›Paper›PMID 29861830›Full record

ArticleOxidative medicine and cellular longevity2018

Methionine Sulfoxide Reductase B1 Regulates Hepatocellular Carcinoma Cell Proliferation and Invasion via the Mitogen-Activated Protein Kinase Pathway and Epithelial-Mesenchymal Transition.

Qiang He, Hui Li, Fanzhi Meng, Xiangjun Sun, Xu Feng, Jiang Chen, Libo Li, Jinghua Liu

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

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  8. "Alphabet" Selenoproteins: Their Characteristics and Physiological Roles.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Qiang HeDepartment of Hepatobiliary Surgery, Linyi People's Hospital, 27th of East Jiefang Road, Linyi, Shandong 276000, China.
Hui LiHuman Resource Department, Linyi People's Hospital, 27th of East Jiefang Road, Linyi, Shandong 276000, China.
Fanzhi MengDepartment of Hepatobiliary Surgery, Linyi People's Hospital, 27th of East Jiefang Road, Linyi, Shandong 276000, China.
Xiangjun SunDepartment of Hepatobiliary Surgery, Linyi People's Hospital, 27th of East Jiefang Road, Linyi, Shandong 276000, China.
Xu FengDepartment of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China.
Jiang ChenDepartment of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China.
Libo LiDepartment of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China.
Jinghua LiuDepartment of Hepatobiliary Surgery, Linyi People's Hospital, 27th of East Jiefang Road, Linyi, Shandong 276000, China.ORCID 0000-0002-8052-1433
Linyi People's Hospital · CNSir Run Run Shaw Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methionine sulfoxide reductase B1 (MsrB1) is a member of the selenoprotein family, which contributes to the reduction of methionine sulfoxides produced from reactive oxygen species (ROS) by redox processes in energy pathways. However, few studies have examined the role of MsrB1 in human hepatocellular carcinoma (HCC). We observed that MsrB1 is highly expressed in HCC tissues and that its expression correlated with the prognoses of patients with HCC after hepatectomy.

Indexed as

Epithelial-Mesenchymal TransitionMAP Kinase Signaling SystemAnimalsCarcinoma, HepatocellularCell Line, TumorCell MovementCell ProliferationCytoskeletonFemaleHumansLiver NeoplasmsMaleMethionine Sulfoxide ReductasesMiceMice, Inbred BALB CMice, Nudemethionine sulfoxide reductaseMethionine Sulfoxide ReductasesRNA, Small Interfering

Identifiers

PMID29861830
PMCPMC5971335
OpenAlexW2801680731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.