Evidence map›Paper›PMID 29861802›Full record

SynthesisPain research & management2018

Low-Level Laser Therapy for Temporomandibular Disorders: A Systematic Review with Meta-Analysis.

Gang-Zhu Xu, Jie Jia, Lin Jin, Jia-Heng Li, Zhan-Yue Wang, Dong-Yuan Cao

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Pain research & management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06419738 (Clinical, Psychosocial, Behavioral Characteristics and Treatment Effectiveness of Low Level Laser Therapy on Patients With Temporomandibular Joint Disorders), which is not on this map. Cited by 39 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 6 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06419738 nacompletednot on this mapstarted 2023, after this paper: background citation

Clinical, Psychosocial, Behavioral Characteristics and Treatment Effectiveness of Low Level Laser Therapy on Patients With Temporomandibular Joint Disorders

TypeinterventionalSponsorHanoi Medical UniversityRan2023 to 2025Enrolled66ConditionsTemporomandibular Joint Disorders, Facial PainArmsSelf-Management Program, Low level laser therapy combined with Self-Management Program, Occlusal Splint combined with Self-Management Program
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 6 syntheses or guidelines pooled it, 123 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Gang-Zhu XuKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, Research Center of Stomatology, College of Stomatology, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Jie JiaDepartment of Psychiatry, Xi'an Mental Health Center, Xi'an, Shaanxi, China.
Lin JinDepartment of Neurosurgery, First Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi, China.
Jia-Heng LiKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, Research Center of Stomatology, College of Stomatology, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Zhan-Yue WangKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, Research Center of Stomatology, College of Stomatology, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Dong-Yuan CaoKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, Research Center of Stomatology, College of Stomatology, Xi'an Jiaotong University, Xi'an, Shaanxi, China.ORCID 0000-0002-3994-2885
Stomatology Hospital · CNXi'an Medical University · CNXian Mental Health Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: We systematically reviewed randomized controlled trials (RCTs) of the effect of low-level laser therapy (LLLT) versus placebo in patients with temporomandibular disorder (TMD). Methods: A systematic search of multiple online sources electronic databases was undertaken. The methodological quality of each included study was assessed using the modified Jadad scale, and the quality of evidence was evaluated using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system. Results: A total of 31 RCTs were included. Total modified Jadad scale scores showed that the methodological quality was high in 30 studies and low in 1 study. Combining data from all clinically heterogeneous studies revealed positive effects of LLLT on pain relief, regardless of the visual analogue scale (VAS) score or the change of VAS score between the baseline and the final follow-up time point, while dosage analyses showed discrepant results about the effects of high or low doses for patients with TMD. Follow-up analyses showed that LLLT significantly reduced pain at the short-term follow-up. Temporomandibular joint function outcomes indicated that the overall effect favored LLLT over placebo. Conclusion: This systematic review suggests that LLLT effectively relieves pain and improves functional outcomes in patients with TMD.

Indexed as

Follow-Up StudiesHumansLaser TherapyOutcome Assessment, Health CareRandomized Controlled Trials as TopicTemporomandibular Joint DisordersVisual Analog Scale

Identifiers

PMID29861802
PMCPMC5971344
OpenAlexW2802967932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.