Evidence map›Paper›PMID 29861791›Full record

ArticleJournal of hematopathology2016

Secondary B-cell lymphoma associated with the Epstein-Barr virus in chronic lymphocytic leukemia patients.

Julie Morscio, Emilie Bittoun, Nathalie Volders, Eveline Lurquin, Iwona Wlodarska, Olivier Gheysens, Peter Vandenberghe, Gregor Verhoef, Philippe Demaerel, Daan Dierickx and 3 more

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of hematopathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Julie Morscio1Department of Imaging and Pathology, Lab for Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium.
Emilie Bittoun1Department of Imaging and Pathology, Lab for Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium.
Nathalie Volders1Department of Imaging and Pathology, Lab for Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium.
Eveline Lurquin2Department of Pathology, University Hospitals Leuven, Leuven, Belgium.
Iwona Wlodarska3Center of Human Genetics, University Hospitals Leuven, Leuven, Belgium.
Olivier Gheysens4Department of Nuclear Medicine, University Hospitals Leuven, Leuven, Belgium.
Peter Vandenberghe3Center of Human Genetics, University Hospitals Leuven, Leuven, Belgium.
Gregor Verhoef5Hematology Department, University Hospitals Leuven, Leuven, Belgium.
Philippe Demaerel6Department of Radiology, University Hospitals Leuven, Leuven, Belgium.
Daan Dierickx5Hematology Department, University Hospitals Leuven, Leuven, Belgium.
Xavier Sagaert1Department of Imaging and Pathology, Lab for Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium.
Ann Janssens5Hematology Department, University Hospitals Leuven, Leuven, Belgium.
Thomas Tousseyn1Department of Imaging and Pathology, Lab for Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium.
KU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Up to 10 % of chronic lymphocytic leukemia (CLL) patients present with aggressive secondary B-cell lymphoma (most frequently diffuse large B-cell lymphoma, DLBCL) which may be clonally related to the CLL (i.e., Richter transformation, RT, 80 % of the cases) or de novo (20 % of the cases). Several genetic lesions associated with RT have already been identified, but the potential role of the Epstein-Barr virus (EBV) has been largely overlooked. In this study, we describe six CLL patients who developed a secondary EBV-positive (EBV

Indexed as

Chronic lymphocytic leukemiaEpstein-Barr virusImmunodeficiency-related lymphomaImmunomodulatory agent-related lymphoproliferationImmunosuppression-related lymphoproliferationRichter transformation

Identifiers

PMID29861791
PMCPMC5962620
OpenAlexW2400166181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.