Evidence map›Paper›PMID 29861600›Full record

ArticleAyu

Effect of

Jyoti Rani, Mahesh P Savalagimath

Open access · greenAbstract read
In one paragraph

Article in Ayu. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jyoti RaniDepartment of Agada Tantra, KLEU's Shri BMK Ayurveda Mahavidyalaya, Belgaum, Karnataka, India.
Mahesh P SavalagimathDepartment of Agada Tantra, KLEU's Shri BMK Ayurveda Mahavidyalaya, Belgaum, Karnataka, India.
KLE Ayur World · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMonosodium glutamate (MSG), an extensively used flavor enhancer, produces degenerative changes in cell and causes neural death which cause imbalance in endocrine system and disturb the body system. While taking consideration of its potency and affinity, it falls under the category of

aimThe aim is to evaluate the efficacy of DVA in MSG-induced female reproductive toxicity in Wistar rats. MATERIALS AND

methodsDVA was prepared and analyzed for preliminary physicochemical, organic and inorganic tests. Twenty-four rats were divided into four groups. Up to 14 days, MSG (0.20g/kg) was given to all groups except control group. From days 15 to 42, DVA (216mg/200g) was given to the third group and in the fourth group no intervention was given to evaluate auto recovery. The second group was considered as disease control. At the end, Follicle-stimu`lating hormone test and histopathology of ovary were done.

resultsThere was a significant increase in primary follicle count and decrease in atretic follicle count in DVA group. Secondary follicle count, tertiary follicle count and Graafian follicle count were increased in DVA group but the increase was not statistically significant.

conclusionMSG mainly acts as a neurotoxic component by oxidative stress. Mostly, the ingredients of DVA have anti-oxidant properties, which counteract the oxidative stress caused by MSG in cell. Many ingredients such as

Indexed as

Anti-oxidantDooshi VishaFollicleneurotoxic

Identifiers

PMID29861600
PMCPMC5954251
OpenAlexW2802427027

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.