Evidence map›Paper›PMID 29861599›Full record

ArticleAyu

Evaluation of anti-inflammatory and antimicrobial activity of AHPL/AYTOP/0213 cream.

Sanjay U Nipanikar, Dheeraj Nagore, Soham S Chitlange, Devashree Buzruk

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ayu. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 7 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sanjay U NipanikarR and D Center, Ari Healthcare Private Limited, Unit No. 401, International Biotech Park, BTS 2 Building, Chrysalis Enclave, 4 Floor, Plot No - 2A, MIDC Phase II, Pimpri, Pune, Maharashtra, India.
Dheeraj NagoreR and D Center, Ari Healthcare Private Limited, Unit No. 401, International Biotech Park, BTS 2 Building, Chrysalis Enclave, 4 Floor, Plot No - 2A, MIDC Phase II, Pimpri, Pune, Maharashtra, India.
Soham S ChitlangeDr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune, Maharashtra, India.
Devashree BuzrukR and D Center, Ari Healthcare Private Limited, Unit No. 401, International Biotech Park, BTS 2 Building, Chrysalis Enclave, 4 Floor, Plot No - 2A, MIDC Phase II, Pimpri, Pune, Maharashtra, India.
Biotech Park · INDr. D. Y. Patil Medical College, Hospital and Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcne vulgaris is almost a widespread disease occurring in all races.

objectiveThe objective of this study is to study anti-inflammatory and antimicrobial activities of AHPL/AYTOP/0213 cream. MATERIALS AND

methodsSkin irritation study was conducted on AHPL/AYTOP/0213 cream as per OECD guidelines. (1) Anti-inflammatory activity: Anti-inflammatory activity of AHPL/AYTOP/0213 cream in comparison with diclofenac sodium cream was assessed in carrageenan-induced rat paw edema model. (2) Antimicrobial activity for

resultsAHPL/AYTOP/0213 cream is nonirritant. Significant reduction in rat paw edema (43%) was observed with AHPL/AYTOP/0213 which was also comparable to diclofenac sodium cream (56.09%). Zone of inhibition for formulation was 20.68 mm, 28.20 mm, and 21.40 mm for

conclusionAHPL/AYTOP/0213 cream is nonirritant and possesses significant anti-inflammatory and antimicrobial activities, which further justifies its role in the management of acne vulgaris.

Indexed as

Acne vulgarisAHPL/AYTOP/0213AntiandrogenicAntibacterialherbal

Identifiers

PMID29861599
PMCPMC5954256
OpenAlexW2802987514

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.