Evidence map›Paper›PMID 29861531›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2018

Reactive Oxygen Species Explicit Dosimetry (ROSED) of a Type 1 Photosensitizer.

Yi Hong Ong, Michele M Kim, Zheng Huang, Timothy C Zhu

Open access · greenAbstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Yi Hong OngDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104.
Michele M KimDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104.
Zheng HuangCenter for Medical Photonics, Fujian Normal University, Fuzhou, China.
Timothy C ZhuDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104.
University of Pennsylvania · USFujian Normal University · CNUniversity of Pennsylvania Health System · US

Funding

TUMOR HYPOXIA, PHOTOSENSITIZER, VASCULARITY AND PDTP01CA087971 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BUSCH, THERESA M, CENGEL, KEITH A · 2001 to 2019
$24.8M
Image-guided treatment planning for pleural Photodynamic TherapyR01CA154562 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ZHU, TIMOTHY C. · 2012 to 2016
$1.6M
NCI NIH HHS P01 CA087971NCI NIH HHS R01 CA154562
6 · The paper itself

Abstract

Type I photodynamic therapy (PDT) is based on the use of photochemical reactions mediated through an interaction between a tumor-selective photosensitizer, photoexcitation with a specific wavelength of light, and production of reactive oxygen species (ROS). The goal of this study is to develop a model to calculate reactive oxygen species concentration ([ROS]

Indexed as

light fluencePDT dosephotodynamic therapyreactive oxygen species explicit dosimetry

Identifiers

PMID29861531
PMCPMC5975967
OpenAlexW2790035912

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.