Evidence map›Paper›PMID 29861526›Full record

ArticleIndian journal of pharmacology

Levetiracetam use during pregnancy in women with epilepsy: Preliminary observations from a tertiary care center in Northern India.

Ramandeep Bansal, Vanita Suri, Seema Chopra, Neelam Aggarwal, Pooja Sikka, Subhas Chandra Saha, Manoj Kumar Goyal, Praveen Kumar

Open access · greenAbstract read
In one paragraph

Article in Indian journal of pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ramandeep BansalDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Vanita SuriDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Seema ChopraDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Neelam AggarwalDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Pooja SikkaDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Subhas Chandra SahaDepartment of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Manoj Kumar GoyalDepartment of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Praveen KumarDepartment of Paediatric Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionData on efficacy and safety of levetiracetam (LEV) during pregnancy is still limited. We analyzed efficacy and safety of LEV during pregnancy in North Indian women with epilepsy (WWE) which is being presented here. PATIENTS AND

methodsThis retrospective study included 99 WWE (on treatment with a single antiepileptic drug [AED]) who were evaluated in medical-surgical disorder antenatal clinic of the department of obstetrics and gynecology at a tertiary care teaching hospital and referral center in North India. All the obstetric and fetal data as well as data pertaining to epilepsy were noted meticulously.

resultsIn this study (

conclusionLEV is a first-line AED during pregnancy. Future prospective studies using therapeutic drug monitoring during pregnancy may further help in establishing its role during pregnancy.

Indexed as

AdultAnticonvulsantsDrug UtilizationEpilepsyFemaleHumansIndiaLevetiracetamMaternal-Fetal ExchangePiracetamPregnancyPregnancy ComplicationsSeizuresTertiary Care CentersTreatment OutcomeYoung AdultAnticonvulsantsLevetiracetamPiracetamLevetiracetampregnancywomen with epilepsy

Identifiers

PMID29861526
PMCPMC5954631
OpenAlexW2800488254

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.