Evidence map›Paper›PMID 29861515›Full record

ArticleJournal of the Medical Association of Thailand = Chotmaihet thangphaet2017

Monitoring HIV Drug Resistance: Early Warning Indicators to Assess Performance of Thailand's Antiretroviral Treatment Program.

Cheewanan Lertpiriyasuwat, Achara Teeraratkul, Yolsilp Suchonwanich, Nartlada Chatharojwong, Kunjanakorn Phokasawad, Porntip Yuktanon, Naparat Pattarapayoon, Sorakij Bhakeecheep, Silvia Bertagnolio, Thierry H Roels and 1 more

Abstract read
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In one paragraph

Article in Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cheewanan LertpiriyasuwatBureau of AIDS, TB and STIs, Department of Disease Control, Thailand Ministry of Public Health, Nonthaburi, Thailand.
Achara TeeraratkulThailand Ministry of Public Health-U.S. Centers for Disease Control and Prevention Collaboration, Division of Global HIV/AIDS and TB, Thailand/Asia Regional Office, Thailand.
Yolsilp SuchonwanichNational Health Security Office, Bangkok, Thailand.
Nartlada ChatharojwongThailand Ministry of Public Health-U.S. Centers for Disease Control and Prevention Collaboration, Division of Global HIV/AIDS and TB, Thailand/Asia Regional Office, Thailand.
Kunjanakorn PhokasawadThailand Ministry of Public Health-U.S. Centers for Disease Control and Prevention Collaboration, Division of Global HIV/AIDS and TB, Thailand/Asia Regional Office, Thailand.
Porntip YuktanonBureau of AIDS, TB and STIs, Department of Disease Control, Thailand Ministry of Public Health, Nonthaburi, Thailand.
Naparat PattarapayoonBureau of AIDS, TB and STIs, Department of Disease Control, Thailand Ministry of Public Health, Nonthaburi, Thailand.
Sorakij BhakeecheepNational Health Security Office, Bangkok, Thailand.
Silvia BertagnolioHIV Department, World Health Organization, Geneva, Switzerland.
Thierry H RoelsThailand Ministry of Public Health-U.S. Centers for Disease Control and Prevention Collaboration, Division of Global HIV/AIDS and TB, Thailand/Asia Regional Office, Thailand.
Sombat ThanprasertsukDepartment of Disease Control, Thailand Ministry of Public Health, Nonthaburi, Thailand.

Funding

CGH CDC HHS U2G GH000616Intramural CDC HHS CC999999World Health Organization 001
6 · The paper itself

Abstract

objectiveTo describe trends in Thailand's antiretroviral treatment (ART) program performance assessed by HIV drug resistance early warning indicators (EWIs), as recommended by WHO, between 2009 and 2013. MATERIAL AND

methodSeven EWIs were monitored, viral load (VL) testing coverage, VL suppression, retention in ART, lost to follow-up (LTFU), antiretrovirals (ARVs) dispensing practices, on-time pill pick-up, and pharmacy stock-outs. Data from ART adult patients in National Health Security Office Scheme were analyzed except for pharmacy stock-outs, which were reported from hospitals. Aggregated averages were calculated for each EWI. Chi-square for trend was applied to measure significant changes.

resultsBy September 2013, 174,284 adults were receiving ART at 929 hospitals. Over time, improvement in VL testing coverage (53.8% in 2009 to 79.8% in 2013) was observed. VL suppression and on-time pill pick up rates were well above 90%. Rates of retention in ART declined from 84.0 to 82.9%, whereas LTFU rates increased from 8.3 to 9.2% (p<0.001). Prescriptions with inappropriate ARVs decreased from 0.32 to 0.10% (p<0.001). Of reporting hospitals, 96.1%, 96.3%, and 96.2% observed no ARVs stock-out between 2011 and 2013.

conclusionEWI is a useful tool to monitor ART program performance and to identify area where improvement is needed.

Indexed as

Anti-Retroviral AgentsDrug Resistance, ViralHIV InfectionsAdolescentAdultHumansThailandAnti-Retroviral AgentsAntiretroviral treatmentDrug resistanceEarly warning indicatorHIVThailand

Identifiers

PMID29861515
PMCPMC5978419

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.