Evidence map›Paper›PMID 29861488›Full record

ArticleNutrients2018

Protective Effect of Aplysin Supplementation on Intestinal Permeability and Microbiota in Rats Treated with Ethanol and Iron.

Yan Ma, Ruiying Li, Ying Liu, Man Liu, Hui Liang

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
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  6. Food science & nutrition · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yan MaDepartment of Human Nutrition, College of Public Health, Qingdao University, 38 Dengzhou Road, Qingdao 266021, China. mayanaa@163.com.
Ruiying LiDepartment of Human Nutrition, College of Public Health, Qingdao University, 38 Dengzhou Road, Qingdao 266021, China. liruiying1104@163.com.
Ying LiuBasic Medical College, Qingdao University of Medicine, 308 Ningxia Road, Qingdao 266071, China. shenghua005@163.com.
Man LiuDepartment of Human Nutrition, College of Public Health, Qingdao University, 38 Dengzhou Road, Qingdao 266021, China. lium_summer@126.com.
Hui LiangDepartment of Human Nutrition, College of Public Health, Qingdao University, 38 Dengzhou Road, Qingdao 266021, China. qdlianghui@126.com.
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aplysin, a kind of phytochemicals or phytonutrients, is purified from red alga Laurencia tristicha. The present study aims to investigate the influence of aplysin on changes of intestinal permeability and microbiota induced by excessive ethanol and iron. Thirty male rats were randomly divided into three groups (10/group): control group (normal saline); ethanol + iron group as EI treated with ethanol (8⁻12 mL/kg/day) and iron (1000 mg/kg) in diet; EI supplemented with aplysin (150 mg/kg/day) group as AEI; the trial lasts for 12 weeks. The result showed that levels of plasma endotoxin, fatty acid-binding protein 2, D-lactic acid, diamine oxidase were increased in rats in the EI group; and significantly decreased by 14%, 17%, 26%, 16%, respectively (

Indexed as

Dietary SupplementsGastrointestinal MicrobiomeAlcohol DrinkingAnimalsCation Transport ProteinsDysbiosisEnteritisFerroportinGastrointestinal AgentsHydrocarbons, BrominatedIntestinal MucosaIntestine, SmallIron, DietaryMaleMicroscopy, Electron, TransmissionOxidative StressaplysinCation Transport ProteinsFerroportinGastrointestinal AgentsHydrocarbons, BrominatedIron, DietaryProtective AgentsSesquiterpenesSolute Carrier Family 11, Member 2aplysinethanolintestinal permeabilityironmicrobiota

Identifiers

PMID29861488
PMCPMC6024731
OpenAlexW2804789056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.