ArticleNeuron2018
Active Sampling State Dynamically Enhances Olfactory Bulb Odor Representation.
Article in Neuron, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed.
- Target-dependent routing of sensory information in the olfactory system.Communications biology · 2026Article
- Perception and neural representation of intermittent odor stimuli in mice.Nature communications · 2026Article
- Odor identity decoding by mitral/tufted cells in the olfactory bulb from large-scale pooled datasets.iScience · 2026Article
- The human brain modulates sniffs according to fine-grained perceptual features of odours.Nature human behaviour · 2026Article
- Fast updating feedback from piriform cortex to the olfactory bulb relays multimodal identity and reward contingency signals during rule-reversal.Nature communications · 2025Article
- How do mammals convert dynamic odor information into neural maps for landscape navigation?PLoS biology · 2024Article
- Odor representation and coding by the mitral/tufted cells in the olfactory bulb.Journal of Zhejiang University. Science. B · 2024Review
- Wireless monitoring of respiration with EEG reveals relationships between respiration, behavior, and brain activity in freely moving mice.Journal of neurophysiology · 2024Article
- Article
- Value-related learning in the olfactory bulb occurs through pathway-dependent perisomatic inhibition of mitral cells.PLoS biology · 2024Article
- Stimulus-Induced Theta-Band LFP Oscillations Format Neuronal Representations of Social Chemosignals in the Mouse Accessory Olfactory Bulb.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Fast updating feedback from piriform cortex to the olfactory bulb relays multimodal reward contingency signals during rule-reversal.bioRxiv : the preprint server for biology · 2023Article
- Social odor discrimination and its enhancement by associative learning in the hippocampal CA2 region.Neuron · 2023Article
- Robust odor identification in novel olfactory environments in mice.Nature communications · 2023Article
- Organization and engagement of a prefrontal-olfactory network during olfactory selective attention.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Long-range functional loops in the mouse olfactory system and their roles in computing odor identity.Neuron · 2022Article
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- Article
- Striatal hub of dynamic and stabilized prediction coding in forebrain networks for olfactory reinforcement learning.Nature communications · 2022Article
- Coupling of Mouse Olfactory Bulb Projection Neurons to Fluctuating Odor Pulses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
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Authors and funding
4 authors.
Funding
Abstract
The olfactory bulb (OB) is the first site of synaptic odor information processing, yet a wealth of contextual and learned information has been described in its activity. To investigate the mechanistic basis of contextual modulation, we use whole-cell recordings to measure odor responses across rapid learning episodes in identified mitral/tufted cells (MTCs). Across these learning episodes, diverse response changes occur already during the first sniff cycle. Motivated mice develop active sniffing strategies across learning that robustly correspond to the odor response changes, resulting in enhanced odor representation. Evoking fast sniffing in different behavioral states demonstrates that response changes during active sampling exceed those predicted from feedforward input alone. Finally, response changes are highly correlated in tufted cells, but not mitral cells, indicating there are cell-type-specific effects on odor representation during active sampling. Altogether, we show that active sampling is strongly associated with enhanced OB responsiveness on rapid timescales.
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