Evidence map›Paper›PMID 29861115›Full record

ArticleAtencion primaria

[Effectiveness of an intervention strategy in the biosimilar glargine prescription pattern in primary care].

Carmen Saborido-Cansino, Bernardo Santos-Ramos, Carmen Carmona-Saucedo, María Victoria Rodríguez-Romero, Antonio González-Martín, Ana Palma-Amaro, Isabel María Rojas-Lucena, Carmen Almeida-González, Susana Sánchez-Fidalgo

Open access · goldAbstract read
In one paragraph

Article in Atencion primaria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Carmen Saborido-CansinoServicio de Farmacia, Área de Gestión Sanitaria Sur, Sevilla, España.
Bernardo Santos-RamosServicio de Farmacia, Hospital Universitario Virgen del Rocío, Sevilla, España.
Carmen Carmona-SaucedoUGC Arahal-Paradas, Arahal, Sevilla, España.
María Victoria Rodríguez-RomeroUGC Alcalá de Guadaira, Centro de Salud Don Paulino García Donas, Alcalá de Guadaira, Sevilla, España.
Antonio González-MartínUGC San Hilario, Centro de Salud San Hilario, Dos Hermanas, Sevilla, España.
Ana Palma-AmaroUGC Dos Hermanas, Centro de Salud Los Montecillos , Dos Hermanas, Sevilla, España.
Isabel María Rojas-LucenaUGC Los Palacios, Centro de Salud San Isidro, Los Palacios y Villafranca, Sevilla, España.
Carmen Almeida-GonzálezBioestadística, Hospital Universitario Valme, Sevilla, España; Departamento de Medicina Preventiva y Salud Pública, Universidad de Sevilla, Sevilla, España.
Susana Sánchez-FidalgoDepartamento de Medicina Preventiva y Salud Pública, Universidad de Sevilla, Sevilla, España. Electronic address: fidalgo@us.es.
Hospital Universitario de Valme · ESHospital Universitario Virgen del Rocío · ESInstituto Palacios · ESUniversidad de Sevilla · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo examine the effects of specific interventions on biosimilar glargine insulin (BGI) prescribing in general practices and to analyse the influence of prescriber and economic impact.

designNon randomized controlled study.

settingGeneral practices in 2 health areas of Seville, intervention and control group.

participants220 general practices (intervention group) and 100 general practices (control group).

interventionIntervention group received educational seminars on biosimilar drugs, pharmacotherapeutic bulletin and prescribing feedback. The study was carried out from the biosimilar commercialization, October-2015, to February-2016 (pre-intervention) and from February to August 2016 (intervention). MAIN MEASUREMENTS: Percentage of patients and DDD with BGI respect to total glargine before and during intervention for both areas were analysed. Physicians have been analysed by subgroups of age, sex, training, type of contract, years of experience and quota. MAIN

resultsBoth indicators for intervention group were significantly greater than for control group (P<.0005), with a 95% confidence interval (2.5-4.7). The ratio of the percentage of cumulative increase of both variables between areas was 3.73 times higher after the intervention. No differences were found for the evaluated categories of physicians in the intervention group.

conclusionsIntervention strategies aimed at training and information, as well as monitoring health professionals, influence the pattern of prescription and can have an economic impact. Our results have not been influenced by the profile of the prescriber.

Indexed as

Practice Patterns, Physicians'Primary Health CareAdultBiosimilar PharmaceuticalsDrug PrescriptionsDrug UtilizationFemaleHumansHypoglycemic AgentsInsulin GlargineMaleMiddle AgedBiosimilar PharmaceuticalsHypoglycemic AgentsInsulin GlargineAtención primariaBiosimilarGlarginaGlargineIntervenciónInterventionPrimary care

Identifiers

PMID29861115
PMCPMC6839203
OpenAlexW2806582524

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.