Evidence map›Paper›PMID 29860903›Full record

ArticleCell transplantation2018

Difference in Serum Endostatin Levels in Diabetic Patients with Critical Limb Ischemia Treated by Autologous Cell Therapy or Percutaneous Transluminal Angioplasty.

Andrea Nemcova, Alexandra Jirkovska, Michal Dubsky, Libor Kolesar, Robert Bem, Vladimira Fejfarova, Anna Pysna, Veronika Woskova, Jelena Skibova, Edward B Jude

Open access · goldAbstract read
In one paragraph

Article in Cell transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Andrea Nemcova1 Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Alexandra Jirkovska1 Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Michal Dubsky1 Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Libor Kolesar2 Department of Immunogenetics, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Robert Bem1 Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Vladimira Fejfarova1 Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Anna Pysna1 Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Veronika Woskova1 Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Jelena Skibova1 Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Edward B Jude3 Diabetes Centre, Tameside Hospital NHS Foundation Trust and University of Manchester, Lancashire, UK.
Institute of Clinical and Experimental Medicine · CZTameside Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to compare the serum levels of the anti-angiogenic factor endostatin (S-endostatin) as a potential marker of vasculogenesis after autologous cell therapy (ACT) versus percutaneous transluminal angioplasty (PTA) in diabetic patients with critical limb ischemia (CLI). A total of 25 diabetic patients with CLI treated in our foot clinic during the period 2008-2014 with ACT generating potential vasculogenesis were consecutively included in the study; 14 diabetic patients with CLI who underwent PTA during the same period were included in a control group in which no vasculogenesis had occurred. S-endostatin was measured before revascularization and at 1, 3, and 6 months after the procedure. The effect of ACT and PTA on tissue ischemia was confirmed by transcutaneous oxygen pressure (TcPO

Indexed as

AngioplastyStem Cell TransplantationAgedAntigens, CD34Cell- and Tissue-Based TherapyDiabetes Mellitus, Type 2Diabetic FootEndostatinsExtremitiesFemaleHumansIschemiaMaleMiddle AgedNeovascularization, PhysiologicPeripheral Vascular DiseasesAntigens, CD34Endostatinsangiogenic factorsautologous cell therapycritical limb ischemiaendostatin

Identifiers

PMID29860903
PMCPMC6168989
OpenAlexW2807569122

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.