Evidence map›Paper›PMID 29860876›Full record

ArticleExpert opinion on therapeutic targets2018

The macrophage as a Trojan horse for antisense oligonucleotide delivery.

James S Novak, Jyoti K Jaiswal, Terence A Partridge

Abstract readEditorial
In one paragraph

Article in Expert opinion on therapeutic targets, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Trojan Horses: A Secret Route for Nanomedicines.Current pharmaceutical biotechnology · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

James S Novaka Center for Genetic Medicine Research, Children's Research Institute , Children's National Health System , Washington, DC , USA.
Jyoti K Jaiswala Center for Genetic Medicine Research, Children's Research Institute , Children's National Health System , Washington, DC , USA.
Terence A Partridgea Center for Genetic Medicine Research, Children's Research Institute , Children's National Health System , Washington, DC , USA.

Funding

Research_ProjectU54HD090257 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI VITTORIO GALLO, VITTORIO GALLO VITTORIO GALLO · 2016 to 2020
$5.9M
Understanding the mechanism and role of cell membrane repair in Miyoshi MyopathyR01AR055686 · NIAMS · ROCKEFELLER UNIVERSITY · PI JAISWAL, JYOTI K · 2008 to 2021
$3.6M
Genetics and Genomics of Muscle Postdoctoral Training ProgramT32AR056993 · NIAMS · CHILDREN'S RESEARCH INSTITUTE · PI JAISWAL, JYOTI K, PARTRIDGE, TERENCE A · 2010 to 2019
$2.2M
Cellular and genomic measures of stem cell function in age-related human muscle atrophyR21AG051260 · NIA · CHILDREN'S RESEARCH INSTITUTE · PI PARTRIDGE, TERENCE A · 2016 to 2017
$481k
NIAMS NIH HHS R01 AR055686NIAMS NIH HHS T32 AR056993NIA NIH HHS R21 AG051260NICHD NIH HHS U54 HD090257
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsGenetic TherapyGene Transfer TechniquesHumansMacrophagesOligonucleotides, AntisenseOligonucleotides, Antisenseantisense oligonucleotidesdrug deliveryDuchenne muscular dystrophyexon skippingmacrophagessatellite cells

Identifiers

PMID29860876
PMCPMC6309535

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.