Evidence map›Paper›PMID 29860785›Full record

ArticleJournal of movement disorders2018

Prospective Characterization of Cognitive Function in Typical and 'Brainstem Predominant'Progressive Supranuclear Palsy Phenotypes.

Young-Eun C Lee, David R Williams, Jacqueline F I Anderson

Abstract read
In one paragraph

Article in Journal of movement disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Pathomechanisms of cognitive impairment in progressive supranuclear palsy.Journal of neural transmission (Vienna, Austria : 1996) · 2023
    Review
  6. Clinical Spectrum of Tauopathies.Frontiers in neurology · 2022
    Review
  7. Review
  8. "Parkinson's disease" on the way to progressive supranuclear palsy: a review on PSP-parkinsonism.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Young-Eun C LeeMelbourne School of Psychological Sciences, The University of Melbourne, Melbourne, Australia.
David R WilliamsDepartment of Neurology, The Alfred Hospital, Melbourne, Australia.
Jacqueline F I AndersonMelbourne School of Psychological Sciences, The University of Melbourne, Melbourne, Australia.ORCID https://orcid.org/0000-0003-4996-8189

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveClinicopathological studies over the last decade have broadened the clinical spectrum of progressive supranuclear palsy (PSP) to include several distinct clinical syndromes. We examined the cognitive profiles of patients with PSP-Richardson's syndrome (PSP-RS) and two atypical 'brainstem predominant' PSP phenotypes (PSP-parkinsonism, PSP-P; and PSP-pure akinesia with gait freezing, PSP-PAGF) using a comprehensive neuropsychological battery.

methodsFourteen patients diagnosed as PSP-RS, three patients with PSP-P and four patients with PSP-PAGF were assessed using a comprehensive battery of neuropsychological tests.

resultsThe typical PSP-RS subgroup demonstrated greater impairments in processing speed [t(19) = -4.10,

conclusionThis is the first prospective study to demonstrate that PSP-RS and 'brainstem predominant' PSP phenotypes can be differentiated on cognitive grounds. These differences correspond with variations in pathological profiles reported in the literature.

Indexed as

cognitionneuropsychologyphenotypesProgressive supranuclear palsy

Identifiers

PMID29860785
PMCPMC5990903

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