Evidence map›Paper›PMID 29860747›Full record

ArticleClinical endoscopy2018

Long-Term Survival and Tumor Recurrence in Patients with Superficial Esophageal Cancer after Complete Non-Curative Endoscopic Resection: A Single-Center Case Series.

Ji Wan Lee, Charles J Cho, Do Hoon Kim, Ji Yong Ahn, Jeong Hoon Lee, Kee Don Choi, Ho June Song, Sook Ryun Park, Hyun Joo Lee, Yong Hee Kim and 5 more

Abstract read
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In one paragraph

Article in Clinical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ji Wan LeeDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Charles J ChoDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Do Hoon KimDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Ji Yong AhnDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Jeong Hoon LeeDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Kee Don ChoiDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Ho June SongDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Sook Ryun ParkDepartment of Oncology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Hyun Joo LeeDepartment of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Yong Hee KimDepartment of Thoracic and Cardiovascular Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Gin Hyug LeeDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Hwoon-Yong JungDepartment of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Sung-Bae KimDepartment of Oncology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Jong Hoon KimDepartment of Radiation Oncology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Seung-Il ParkDepartment of Thoracic and Cardiovascular Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

Funding

TRAINING IN THE IMMUNOBIOLOGY AND MOLECULAR CELL BIOLOGY OF CANCERT32CA009547 · NCI · WASHINGTON UNIVERSITY · PI ROBERT DAVID SCHREIBER · 1986 to 2026
$12.1M
NCI NIH HHS T32 CA009547
6 · The paper itself

Abstract

BACKGROUND/

aimsTo report the long-term survival and tumor recurrence outcomes in patients with superficial esophageal cancer (SEC) after complete non-curative endoscopic resection (ER).

methodsWe retrieved ER data for 24 patients with non-curatively resected SEC. Non-curative resection was defined as the presence of submucosal and/or lymphovascular invasion on ER pathology. Relevant clinical and tumor-specific parameters were reviewed.

resultsThe mean age of the 24 study patients was 66.3±8.3 years. Ten patients were closely followed up without treatment, while 14 received additional treatment. During a mean follow-up of 59.0±33.2 months, the 3- and 5-year survival rates of all cases were 90.7% and 77.6%, respectively. The 5-year overall survival rates were 72.9% in the close observation group and 82.1% in the additional treatment group (p=0.958). The 5-year cumulative incidences of all cases of recurrence (25.0% vs. 43.3%, p=0.388), primary EC recurrence (10.0% vs. 16.4%, p=0.558), and metachronous EC recurrence (16.7% vs. 26.7%, p=0.667) were similar between the two groups.

conclusionPatients with non-curatively resected SEC showed good long-term survival outcomes. Given the similar oncologic outcomes, close observation may be an option with appropriate caution taken for patients who are medically unfit to receive additional therapy.

Indexed as

Endoscopic resectionEsophageal carcinomaRecurrenceSurvival

Identifiers

PMID29860747
PMCPMC6182292

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.