Evidence map›Paper›PMID 29860556›Full record

ArticleAIDS and behavior2018

Longitudinal Effects of Syndemics on ART Non-adherence Among Sexual Minority Men.

Audrey Harkness, Sierra A Bainter, Conall O'Cleirigh, Noelle A Mendez, Kenneth H Mayer, Steven A Safren

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Audrey HarknessDepartment of Psychology, University of Miami, Clinical Research Building (C-204), 1120 NW 14th Street, Suite 786, Miami, FL, 33136, USA. aharkness@miami.edu.ORCID http://orcid.org/0000-0003-2290-9904
Sierra A BainterDepartment of Psychology, University of Miami, Clinical Research Building (C-204), 1120 NW 14th Street, Suite 786, Miami, FL, 33136, USA.
Conall O'CleirighFenway Community Health, The Fenway Institute, Boston, MA, USA.
Noelle A MendezDepartment of Psychology, University of Miami, Clinical Research Building (C-204), 1120 NW 14th Street, Suite 786, Miami, FL, 33136, USA.
Kenneth H MayerFenway Community Health, The Fenway Institute, Boston, MA, USA.
Steven A SafrenDepartment of Psychology, University of Miami, Clinical Research Building (C-204), 1120 NW 14th Street, Suite 786, Miami, FL, 33136, USA.
University of Miami · USBeth Israel Deaconess Medical Center · USHarvard University · US

Funding

Enhancing HIV Prevention Among High-Risk HIV+ MenR01MH068746 · NIMH · FENWAY COMMUNITY HEALTH CENTER · PI MAYER, KENNETH H · 2003 to 2007
$2.8M
Addressing psychosocial comorbidities in HIV treatment and preventionK24DA040489 · NIDA · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2016 to 2020
$931k
Health Resources and Services Administration H97HA01293National Institute of Mental Health 5R01MH068746National Institute on Drug Abuse 9K24DA040489NIDA NIH HHS K24 DA040489NIMH NIH HHS R01 MH068746
6 · The paper itself

Abstract

This study examined longitudinally the additive effect of syndemics, or co-occurring psychosocial problems, on antiretroviral treatment (ART) non-adherence among 390 HIV-positive sexual minority men. Participants completed measures of ART adherence (reduced to a non-adherence score using exploratory factor analysis) and six syndemic conditions. We employed multilevel modeling with the number of syndemics as a longitudinal predictor of non-adherence, and logistic regression with baseline syndemics predicting follow up viral load. Number of syndemics was a significant longitudinal predictor of non-adherence, with each additional syndemic associated with a 0.13 increase in non-adherence (p = 0.004). Each additional syndemic was also associated with 1.27 greater odds of detectable viral load (p = 0.002). Among HIV-positive sexual minority men in this sample, more syndemics were associated with lower ART adherence and greater odds of detectable viral load, suggesting the need for behavioral intervention to facilitate care for this population.

Indexed as

Drug MonitoringSexual and Gender MinoritiesSyndemicAdultAdult Survivors of Child AbuseAlcoholismAnti-Retroviral AgentsAnxiety DisordersChild Abuse, SexualChild, PreschoolComorbidityDepressive DisorderFactor Analysis, StatisticalHIV InfectionsHomosexuality, MaleHumansAnti-Retroviral AgentsAdherenceAntiretroviral therapy/ARTHIVSexual minoritySyndemics

Identifiers

PMID29860556
PMCPMC6628710
OpenAlexW2805685615

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.