Evidence map›Paper›PMID 29860441›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2018

The National Sleep Research Resource: towards a sleep data commons.

Guo-Qiang Zhang, Licong Cui, Remo Mueller, Shiqiang Tao, Matthew Kim, Michael Rueschman, Sara Mariani, Daniel Mobley, Susan Redline

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 325 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
325citing papers in PubMed, 1 pooled it
26.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

325 citing papers in PubMed, 1 synthesis or guideline pooled it, 858 citations in OpenAlex.

  1. Deep learning for EEG-based sleep stage classification: a review.Medical & biological engineering & computing · 2026
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

265 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Guo-Qiang ZhangInstitute for Biomedical Informatics, University of Kentucky, Lexington, Kentucky, USA.
Licong CuiInstitute for Biomedical Informatics, University of Kentucky, Lexington, Kentucky, USA.
Remo MuellerBrigham and Women's Hospital, Boston, Massachusetts, USA.
Shiqiang TaoInstitute for Biomedical Informatics, University of Kentucky, Lexington, Kentucky, USA.
Matthew KimBrigham and Women's Hospital, Boston, Massachusetts, USA.
Michael RueschmanBrigham and Women's Hospital, Boston, Massachusetts, USA.
Sara MarianiBrigham and Women's Hospital, Boston, Massachusetts, USA.
Daniel MobleyBrigham and Women's Hospital, Boston, Massachusetts, USA.
Susan RedlineBrigham and Women's Hospital, Boston, Massachusetts, USA.
Brigham and Women's Hospital · USHarvard University · USUniversity of Kentucky · US

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
National Sleep Research Resource (NSRR)R24HL114473 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI REDLINE, SUSAN S., ZHANG, GUO-QIANG · 2013 to 2017
$7.5M
NCATS NIH HHS UL1 TR001998NHLBI NIH HHS R24 HL114473
6 · The paper itself

Abstract

Objective: The gold standard for diagnosing sleep disorders is polysomnography, which generates extensive data about biophysical changes occurring during sleep. We developed the National Sleep Research Resource (NSRR), a comprehensive system for sharing sleep data. The NSRR embodies elements of a data commons aimed at accelerating research to address critical questions about the impact of sleep disorders on important health outcomes. Approach: We used a metadata-guided approach, with a set of common sleep-specific terms enforcing uniform semantic interpretation of data elements across three main components: (1) annotated datasets; (2) user interfaces for accessing data; and (3) computational tools for the analysis of polysomnography recordings. We incorporated the process for managing dataset-specific data use agreements, evidence of Institutional Review Board review, and the corresponding access control in the NSRR web portal. The metadata-guided approach facilitates structural and semantic interoperability, ultimately leading to enhanced data reusability and scientific rigor. Results: The authors curated and deposited retrospective data from 10 large, NIH-funded sleep cohort studies, including several from the Trans-Omics for Precision Medicine (TOPMed) program, into the NSRR. The NSRR currently contains data on 26 808 subjects and 31 166 signal files in European Data Format. Launched in April 2014, over 3000 registered users have downloaded over 130 terabytes of data. Conclusions: The NSRR offers a use case and an example for creating a full-fledged data commons. It provides a single point of access to analysis-ready physiological signals from polysomnography obtained from multiple sources, and a wide variety of clinical data to facilitate sleep research.

Indexed as

Biomedical ResearchDatasets as TopicInformation DisseminationPolysomnographySleep Wake DisordersCohort StudiesCommon Data ElementsComputational BiologyHumansMetadataRetrospective StudiesSystems IntegrationUser-Computer Interface

Identifiers

PMID29860441
PMCPMC6188513
OpenAlexW2805075551

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.