Evidence map›Paper›PMID 29860411›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2019

Chronic Opioid Therapy in People Living With Human Immunodeficiency Virus: Patients' Perspectives on Risks, Monitoring, and Guidelines.

Jonathan Colasanti, Marlene C Lira, Debbie M Cheng, Jane M Liebschutz, Judith I Tsui, Leah S Forman, Meg Sullivan, Alexander Y Walley, Carly Bridden, Christin Root and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Improving the Delivery of Chronic Opioid Therapy Among People Living With Human Immunodeficiency Virus: A Cluster Randomized Clinical Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Chronic Pain Mitigation and Opioid Weaning at a Multidisciplinary AIDS Clinic: A Case Report.Rehabilitation oncology (American Physical Therapy Association. Oncology Section) · 2019
    Article
  14. Article
  15. Discovering major opioid-related research themes over time: A text mining technique.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2019
    Article
  16. Article
  17. Emergency Department Utilization Among People Living With HIV on Chronic Opioid Therapy.Journal of the International Association of Providers of AIDS Care
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Jonathan ColasantiDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
Marlene C LiraClinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center, Massachusetts.
Debbie M ChengDepartment of Biostatistics, Boston University School of Public Health, Massachusetts.
Jane M LiebschutzDivision of General Internal Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pennsylvania.
Judith I TsuiSection of General Internal Medicine, Department of Medicine, University of Washington and Harborview Medical Center, Seattle.
Leah S FormanBiostatistics and Epidemiology Data Analytics Center, Boston University School of Public Health, Massachusetts.
Meg SullivanSection of Infectious Disease, Department of Medicine, Boston University School of Medicine, Massachusetts.
Alexander Y WalleyClinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center, Massachusetts.
Carly BriddenClinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center, Massachusetts.
Christin RootHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Melissa PodolskyClinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center, Massachusetts.
Catherine AbramsHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Kishna OutlawHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Catherine E HarrisHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Wendy S ArmstrongDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
Jeffrey H SametClinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center, Massachusetts.
Carlos Del RioDivision of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
Emory University · USBoston Medical Center · USBoston University · USUniversity of Pittsburgh · USUniversity of Washington · US

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Hannah LF Cooper · 2002 to 2026
$74.0M
Improving Physician Opioid Prescribing for Chronic Pain in HIV-infected PersonsR01DA037768 · NIDA · BOSTON MEDICAL CENTER · PI DEL RIO, CARLOS, SAMET, JEFFREY H. · 2014 to 2018
$5.3M
NIAID NIH HHS P30 AI050409NIDA NIH HHS R01 DA037768
6 · The paper itself

Abstract

Background: Chronic opioid therapy (COT) is common in people living with human immunodeficiency virus (PLHIV), but is not well studied. We assessed opioid risk behaviors, perceptions of risk, opioid monitoring, and associated Current Opioid Misuse Measure (COMM) scores of PLHIV on COT. Methods: COT was defined as ≥3 opioid prescriptions ≥21 days apart in the past 6 months. Demographics, substance use, COMM score, and perceptions of and satisfaction with COT monitoring were assessed among PLHIV on COT from 2 HIV clinics. Results: Among participants (N = 165) on COT, 66% were male and 72% were black, with a median age of 55 (standard deviation, 8) years. Alcohol and drug use disorders were present in 17% and 19%, respectively. In 43%, the COMM score, a measure of potential opioid misuse, was high. Thirty percent had an opioid treatment agreement, 66% a urine drug test (UDT), and 12% a pill count. Ninety percent acknowledged opioids' addictive potential. Median (interquartile range) satisfaction levels (1-10 [10 = highest]) were 10 (7-10) for opioid treatment agreements, 9.5 (6-10) for pill counts, and 10 (8-10) for UDT. No association was found between higher COMM score and receipt of or satisfaction with COT monitoring. Conclusions: Among PLHIV on COT, opioid misuse and awareness of the addictive potential of COT are common, yet COT monitoring practices were not guideline concordant. Patients who received monitoring practices reported high satisfaction. Patient attitudes suggest high acceptance of guideline concordant care for PLHIV on COT when it occurs.

Indexed as

HIV InfectionsAdultAgedAnalgesics, OpioidChronic PainCohort StudiesDrug Administration ScheduleFemaleHumansMaleMiddle AgedOpioid-Related DisordersPractice Guidelines as TopicRisk AssessmentRisk FactorsSubstance Abuse DetectionAnalgesics, Opioid

Identifiers

PMID29860411
PMCPMC6594413
OpenAlexW2806061691

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.