ReviewClinical infectious diseases : an official publication of the Infectious Diseases Society of America2018
Models of Trachoma Transmission and Their Policy Implications: From Control to Elimination.
Review in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- TFOS lifestyle: Impact of societal challenges on the ocular surface.The ocular surface · 2023Pooled it
- Macrolide and Nonmacrolide Resistance with Mass Azithromycin Distribution.The New England journal of medicine · 2020Trial
- Dynamics of trachoma infection in West Africa revealed by a hidden state model.PLoS computational biology · 2026Article
- Spread of the plague in Venice, 1630-1631: epidemic entropy in a "natural experiment".medRxiv : the preprint server for health sciences · 2025Article
- Article
- A Review on the Epidemiology and Clinical Management of Neglected Tropical Diseases.Infectious disorders drug targets · 2025Review
- Etiologies of Infectious Keratitis in Malawi.The American journal of tropical medicine and hygiene · 2024Article
- District-Level Forecast of Achieving Trachoma Elimination as a Public Health Problem By 2030: An Ensemble Modelling Approach.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Trachoma risk factors in Oromia Region, Ethiopia.PLoS neglected tropical diseases · 2023Article
- Modeling the "F" in "SAFE": The dynamic game of facial cleanliness in trachoma prevention.PloS one · 2023Article
- Forecasting the elimination of active trachoma: An empirical model.PLoS neglected tropical diseases · 2022Article
- Surveillance for peri-elimination trachoma recrudescence: Exploratory studies in Ghana.PLoS neglected tropical diseases · 2021Article
- Implementing trachoma control programmes in marginalised populations in Tanzania: A qualitative study exploring the experiences and perspectives of key stakeholders.PLoS neglected tropical diseases · 2021Article
- Practical Guidance for Clinical Microbiology Laboratories: Diagnosis of Ocular Infections.Clinical microbiology reviews · 2021Review
- What Can Modeling Tell Us About Sustainable End Points for Neglected Tropical Diseases?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Forecasting Trachoma Control and Identifying Transmission-Hotspots.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Modelling trachoma post-2020: opportunities for mitigating the impact of COVID-19 and accelerating progress towards elimination.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2021Article
- Effectiveness and safety of azithromycin 1.5% eye drops for mass treatment of active trachoma in a highly endemic district in Cameroon.BMJ open ophthalmology · 2020Article
- Progress to Eliminate Trachoma as a Public Health Problem in Amhara National Regional State, Ethiopia: Results of 152 Population-Based Surveys.The American journal of tropical medicine and hygiene · 2019Article
- Toward the Elimination of Disease: the 2019 Weisenfeld Award Lecture.Investigative ophthalmology & visual science · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Despite great progress in eliminating trachoma from the majority of worldwide districts, trachoma control seems to have stalled in some endemic districts. Can mathematical models help suggest the way forward? We review specific achievements of models in trachoma control in the past. Models showed that, even with incomplete coverage, mass drug administration could eliminate disease through a spillover effect, somewhat analogous to how incomplete vaccine campaigns can eliminate disease through herd protection. Models also suggest that elimination can always be achieved if enough people are treated often enough with an effective enough drug. Other models supported the idea that targeting ages at highest risk or continued improvements in hygiene and sanitation can contribute meaningfully to trachoma control. Models of intensive targeting of a core group may point the way to final eradication even in areas with substantial transmission and within-community heterogeneity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.