Evidence map›Paper›PMID 29859928›Full record

ArticleCellular signalling2018

Phospholipase C delta 4 (PLCδ4) is a nuclear protein involved in cell proliferation and senescence in mesenchymal stromal stem cells.

Marianna Kunrath-Lima, Marcelo Coutinho de Miranda, Andrea da Fonseca Ferreira, Camila Cristina Fraga Faraco, Mariane Izabella Abreu de Melo, Alfredo Miranda Goes, Michele Angela Rodrigues, Jerusa Araújo Quintão Arantes Faria, Dawidson Assis Gomes

Abstract read
In one paragraph

Article in Cellular signalling, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Sprayed PAA-CaORegenerative biomaterials · 2023
    Article
  8. The basis of nuclear phospholipase C in cell proliferation.Advances in biological regulation · 2021
    Review
  9. Review
  10. Review
  11. The nuclear phosphoinositide response to stress.Cell cycle (Georgetown, Tex.) · 2020
    Review
  12. Phospholipase C.Advances in experimental medicine and biology · 2020
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Marianna Kunrath-LimaDepartamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Marcelo Coutinho de MirandaDepartamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Andrea da Fonseca FerreiraDepartamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Camila Cristina Fraga FaracoDepartamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Mariane Izabella Abreu de MeloDepartamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Alfredo Miranda GoesDepartamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Michele Angela RodriguesDepartamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Jerusa Araújo Quintão Arantes FariaDepartamento de Ciências Fisiológicas, Instituto de Ciências Biológicas, Universidade Federal do Amazonas, Manaus, AM, Brazil.
Dawidson Assis GomesDepartamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil. Electronic address: dawidson@icb.ufmg.br.
Universidade Federal de Minas Gerais · BRUniversidade Federal do Amazonas · BR

Funding

Trafficking of the EGF receptor to the nucleus: Mechanisms and EffectsR03TW008709 · FIC · YALE UNIVERSITY · PI NATHANSON, MICHAEL H · 2012 to 2014
$230k
FIC NIH HHS R03 TW008709
6 · The paper itself

Abstract

Ca

Indexed as

Cell ProliferationCellular SenescenceAdipose TissueCell Cycle CheckpointsCells, CulturedCyclin-Dependent Kinase Inhibitor p16Cyclin-Dependent Kinase Inhibitor p21HumansMesenchymal Stem CellsPhospholipase C deltaReactive Oxygen SpeciesRNA InterferenceRNA, Small InterferingCyclin-Dependent Kinase Inhibitor p16Cyclin-Dependent Kinase Inhibitor p21Phospholipase C deltaReactive Oxygen SpeciesRNA, Small InterferingCalcium signalingCellular proliferationCellular senescenceHuman PLCδ4Nuclear calcium signaling

Identifiers

PMID29859928
PMCPMC6095203
OpenAlexW2806654837

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.