ReviewJournal of nanobiotechnology2018
Critical review of the safety assessment of titanium dioxide additives in food.
Review in Journal of nanobiotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed.
- Dietary Titanium Dioxide (E171) Alters the Colon Transcriptome-Evidence From a Human Dietary Intervention Study.Molecular nutrition & food research · 2026Trial
- Co-Exposure to Food-Grade and Nano-TiOToxics · 2026Article
- Article
- Selective adsorption of metabolites by different size of TiOFood chemistry: X · 2025Article
- Color additives in chewing gum products sold through Indian online marketplaces: variances and compliance with food safety norms in India, the EU, and the USA.BMC nutrition · 2025Article
- Beneath the Surface: The Emerging Role of Ultra-Processed Foods in Obesity-Related Cancer.Current oncology reports · 2025Review
- Emerging 3D printing technologies for solid oral dosage forms: Processes, materials and analytical tools for real-time assessment.International journal of pharmaceutics · 2025Review
- Effects of the Interactions Between Food Additive Titanium Dioxide and Matrices on Genotoxicity.International journal of molecular sciences · 2025Article
- Inorganic dietary nanoparticles in intestinal barrier function of inflammatory bowel disease: allies or adversaries?Frontiers in immunology · 2025Review
- Investigating the ROS Formation and Particle Behavior of Food-Grade Titanium Dioxide (E171) in the TIM-1 Dynamic Gastrointestinal Digestion Model.Nanomaterials (Basel, Switzerland) · 2024Article
- Exposure to a Titanium Dioxide Product Alters DNA Methylation in Human Cells.Nanomaterials (Basel, Switzerland) · 2024Article
- Titanium dioxide in face powders and eyeshadows: Developing an analytical methodology for accessing customer safety.Journal of cosmetic dermatology · 2024Article
- Genome-wide DNA methylation sequencing reveals the involvement of ferroptosis in hepatotoxicity induced by dietary exposure to food-grade titanium dioxide.Particle and fibre toxicology · 2024Article
- Enhanced intestinal epithelial co-culture model with orbital mechanical stimulation: a proof-of-concept application in food nanotoxicology.Frontiers in molecular biosciences · 2024Article
- Maternal exposure to nano-titanium dioxide impedes fetal development via endothelial-to-mesenchymal transition in the placental labyrinth in mice.Particle and fibre toxicology · 2023Article
- Titanium Dioxide (TiOToxics · 2023Article
- Perinatal foodborne titanium dioxide exposure-mediated dysbiosis predisposes mice to develop colitis through life.Particle and fibre toxicology · 2023Article
- Comprehensive Analysis of Titanium Oxide Nanoparticle Size and Surface Properties on Neuronal PC-12 Cells: Unraveling Cytotoxicity, Dopaminergic Gene Expression, and Acetylcholinesterase Inhibition.Journal of xenobiotics · 2023Article
- Nanoscatterer-Assisted Fluorescence Amplification Technique.Nanomaterials (Basel, Switzerland) · 2023Article
- Sugarcane Pulp Take-Out Containers Produce More Microparticles in Acidic Foods.Foods (Basel, Switzerland) · 2023Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Nanomaterial engineering provides an important technological advance that offers substantial benefits for applications not only in the production and processing, but also in the packaging and storage of food. An expanding commercialization of nanomaterials as part of the modern diet will substantially increase their oral intake worldwide. While the risk of particle inhalation received much attention, gaps of knowledge exist regarding possible adverse health effects due to gastrointestinal exposure. This problem is highlighted by pigment-grade titanium dioxide (TiO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.