ArticleBMC biology2018
Using in vivo oxidation status of one- and two-component redox relays to determine H
Article in BMC biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Low Temperature Plasma Impairs the Pathogenicity ofFoods (Basel, Switzerland) · 2026Article
- Dissecting the functional and spatial roles of peroxiredoxins as HCellular and molecular life sciences : CMLS · 2026Article
- Cytosolic PRDX1 acts as an extramitochondrial sink to set mitochondrial HRedox biology · 2026Article
- The interactome of the Bakers' yeast peroxiredoxin Tsa1 implicates it in redox regulation of intermediary metabolism, glycolysis, and zinc homeostasis.Metallomics : integrated biometal science · 2025Article
- Scalable, robust, high-throughput expression & purification of nanobodies enabled by 2-stage dynamic control.Metabolic engineering · 2024Article
- Estragole Inhibits Growth and Aflatoxin Biosynthesis ofMicrobiology spectrum · 2023Article
- Current Aspects on the Plastic Nano- and Microparticles Toxicity in Zebrafish-Focus on the Correlation between Oxidative Stress Responses and Neurodevelopment.Animals : an open access journal from MDPI · 2023Review
- Expression of the HAntioxidants (Basel, Switzerland) · 2023Article
- Histone 2-Hydroxyisobutyryltransferase Encoded byToxins · 2022Article
- Putative CToxins · 2022Article
- Monofunctional Heme-Catalases.Antioxidants (Basel, Switzerland) · 2022Review
- Resistance to HRedox biology · 2022Article
- Data Processing to Probe the Cellular Hydrogen Peroxide Landscape.Methods in molecular biology (Clifton, N.J.) · 2022Article
- A comparison of Prx- and OxyR-based HThe Journal of biological chemistry · 2021Article
- The Mitochondria-to-Cytosol HAntioxidants (Basel, Switzerland) · 2021Article
- Dynamics of a Key Conformational Transition in the Mechanism of Peroxiredoxin Sulfinylation.ACS catalysis · 2020Article
- Monitoring cytosolic HNature communications · 2019Article
- Human Aquaporin-5 Facilitates Hydrogen Peroxide Permeation Affecting Adaption to Oxidative Stress and Cancer Cell Migration.Cancers · 2019Article
- Measuring intracellular concentration of hydrogen peroxide with the use of genetically encoded HRedox biology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHydrogen peroxide (H
resultsBy comparing the activation of both systems in fission yeast, and applying mathematical equations to the experimental data, we estimate the toxic threshold of intracellular H
conclusionsBoth Tpx1 and OxyR contain thiol switches, with very high reactivity towards peroxides. Nevertheless, the fast reduction of Tpx1 defines it as a scavenger, and this efficient recycling dramatically changes the Tpx1-Pap1 response to H
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.