Evidence map›Paper›PMID 29858959›Full record

ArticleJournal of biomolecular NMR2018

NMR probing of invisible excited states using selectively labeled RNAs.

Regan M LeBlanc, Andrew P Longhini, Vitali Tugarinov, T Kwaku Dayie

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of biomolecular NMR, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Synthesis of SelectivelyChemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  4. Review
  5. Review
  6. Synthesis of [7-Monatshefte fur chemie · 2022
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. RNA Dynamics by NMR Spectroscopy.Chembiochem : a European journal of chemical biology · 2019
    Review
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Regan M LeBlancDepartment of Chemistry & Biochemistry, University of Maryland, College Park, 8314 Paint Branch Dr, College Park, MD, 20782, USA.
Andrew P LonghiniDepartment of Chemistry & Biochemistry, University of Maryland, College Park, 8314 Paint Branch Dr, College Park, MD, 20782, USA.
Vitali TugarinovLaboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 20892-052, USA.
T Kwaku DayieDepartment of Chemistry & Biochemistry, University of Maryland, College Park, 8314 Paint Branch Dr, College Park, MD, 20782, USA. dayie@umd.edu.ORCID http://orcid.org/0000-0002-7119-4362

Funding

The Center for HIV RNA Studies (CRNA)U54GM103297 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TELESNITSKY, ALICE · 2017 to 2018
$10.2M
Directorate for Biological Sciences DBI1040158NIGMS NIH HHS U54 GM103297NIGMS NIH HHS U54GM103297)
6 · The paper itself

Abstract

Carr-Purcell-Meiboom-Gill (CPMG) relaxation dispersion NMR experiments are invaluable for probing sparsely and transiently populated biomolecular states that cannot be directly detected by traditional NMR experiments and that are invisible by other biophysical approaches. A notable gap for RNA is the absence of CPMG experiments for measurement of methine base

Indexed as

Carbon IsotopesMolecular Dynamics SimulationMolecular ProbesNuclear Magnetic Resonance, BiomolecularRNAStaining and LabelingTime FactorsCarbon-13Carbon IsotopesMolecular ProbesRNAChemical enzymatic labelingMethylene (CH2) TROSY CPMGMultiple quantumProton relaxation dispersionRNA dynamicsStable isotope

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.