Evidence map›Paper›PMID 29858793›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2018

Practical Guidelines for Cerenkov Luminescence Imaging with Clinically Relevant Isotopes.

Nikunj B Bhatt, Darpan N Pandya, William A Dezarn, Frank C Marini, Dawen Zhao, William H Gmeiner, Pierre L Triozzi, Thaddeus J Wadas

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nikunj B BhattDepartment of Cancer Biology, Wake Forest University Health Sciences, Winston-Salem, NC, USA.
Darpan N PandyaDepartment of Cancer Biology, Wake Forest University Health Sciences, Winston-Salem, NC, USA.
William A DezarnDepartment of Radiation Oncology, Wake Forest University Health Sciences, Winston-Salem, NC, USA.
Frank C MariniDepartment of Cancer Biology, Wake Forest University Health Sciences, Winston-Salem, NC, USA.
Dawen ZhaoDepartment of Biomedical Engineering, Wake Forest University Health Sciences, Winston-Salem, NC, USA.
William H GmeinerDepartment of Cancer Biology, Wake Forest University Health Sciences, Winston-Salem, NC, USA.
Pierre L TriozziDepartment of Hematology and Oncology, Wake Forest University Health Sciences, Winston-Salem, NC, USA.
Thaddeus J WadasDepartment of Cancer Biology, Wake Forest University Health Sciences, Winston-Salem, NC, USA. twadas@wakehealth.edu.
Wake Forest University · US

Funding

Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4M
NCI NIH HHS P30 CA012197
6 · The paper itself

Abstract

Cerenkov luminescence imaging (CLI) is a relatively new imaging modality that utilizes conventional optical imaging instrumentation to detect Cerenkov radiation derived from standard and often clinically approved radiotracers. Its research versatility, low cost, and ease of use have increased its popularity within the molecular imaging community and at institutions that are interested in conducting radiotracer-based molecular imaging research, but that lack the necessary resources and infrastructure. Here, we provide a description of the materials and procedures necessary to conduct a Cerenkov luminescence imaging experiment using a variety of imaging instrumentation, radionuclides, and animal models.

Indexed as

Phantoms, ImagingAnimalsHumansLuminescent MeasurementsMiceMultimodal ImagingNeoplasmsPractice Guidelines as TopicRadiopharmaceuticalsRadiopharmaceuticalsAntibodyCerenkov luminescence imagingIsotopeNanoparticleOptical imagingPeptideRadiationRadiotherapyReporter gene expression

Identifiers

PMID29858793
PMCPMC6734187
OpenAlexW2806891004

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.