ArticleRadiological physics and technology2018
Influence of Gd-EOB-DTPA on T1 dependence of the proton density fat fraction using magnetic resonance spectroscopy.
Article in Radiological physics and technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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11 authors at 4 institutions in 1 country.
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Abstract
This phantom study assessed the effect of Gd-EOB-DTPA on T1 bias (difference in T1 between water and fat) of the proton density fat fraction when using magnetic resonance spectroscopy. Phantoms containing varying fat percentages, without and with Gd-EOB-DTPA (precontrast and postcontrast, respectively), were scanned with repetition times ranging from 1000 to 5000 ms. The relationship between the proton density fat fraction at a reference repetition time of 5000 ms and that using different repetition times, was evaluated in the precontrast and postcontrast phantoms using linear regression and Bland-Altman analyses. In the precontrast phantom, as the repetition time increased, the slope tended to approach one. In the postcontrast phantom, the slope and intercept were near one and zero, respectively. The mean difference was smaller in the postcontrast phantom (range - 0.24 to - 0.01%) than in the precontrast phantom (range 0.12 to 3.52%). We conclude that I1 bias is minimized by Gd-EOB-DTPA.
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