Evidence map›Paper›PMID 29858709›Full record

SynthesisCurrent urology reports2018

Erectile Dysfunction and Lower Urinary Tract Symptoms.

Cosimo De Nunzio, Riccardo Lombardo, Giorgia Tema, Andrea Tubaro

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Current urology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Erectile Dysfunction and Oxidative Stress: A Narrative Review.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Cosimo De NunzioDepartment of Urology, Sant'Andrea Hospital, "La Sapienza" University, Via di Grottarossa 1035, 00189, Rome, Italy. cosimodenunzio@virgilio.it.
Riccardo LombardoDepartment of Urology, Sant'Andrea Hospital, "La Sapienza" University, Via di Grottarossa 1035, 00189, Rome, Italy.
Giorgia TemaDepartment of Urology, Sant'Andrea Hospital, "La Sapienza" University, Via di Grottarossa 1035, 00189, Rome, Italy.
Andrea TubaroDepartment of Urology, Sant'Andrea Hospital, "La Sapienza" University, Via di Grottarossa 1035, 00189, Rome, Italy.
Azienda Ospedaliera Sant'Andrea · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewIn the past years, the relationship between lower urinary tract symptoms and erectile dysfunction has been widely explored. The aim of our systematic review is to summarize the published evidence over the past year on lower urinary tract symptoms (LUTS) and erectile dysfunction (ED). RECENT

findingsRecent data support the relationship between LUTS and ED in Eastern Europe and in Asia. The role of phosphodiesterase inhibitors alone or in combination with alpha blockers to treat LUTS and ED, especially in younger patients, is strongly supported by high level of evidence. LUTS and ED are prevalent conditions in men over 50; epidemiologically, the relationship between both conditions has been confirmed all over the world. PDE5i alone or in combination with alpha blockers can be considered the gold standard for the treatment of young patients with storage symptoms and concomitant ED. In clinical research, a better understanding of the molecular pathways behind this association may also help to identify new possible targets and develop novel therapeutic approaches to manage both disorders; the identification of new biomarkers of both disorders is also compulsory in this area.

Indexed as

Adrenergic alpha-AntagonistsErectile DysfunctionHumansLower Urinary Tract SymptomsMalePhosphodiesterase 5 InhibitorsAdrenergic alpha-AntagonistsPhosphodiesterase 5 InhibitorsDiagnosisErectile dysfunctionLUTSOutcomeProstateTreatment

Identifiers

PMID29858709
OpenAlexW2806479085

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.