Evidence map›Paper›PMID 29858679›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2018

Extension of C. elegans lifespan using the ·NO-delivery dinitrosyl iron complexes.

Hsiao-Wen Huang, Yen-Hung Lin, Min-Hsuan Lin, Ya-Rong Huang, Chih-Hung Chou, Hsiao-Chin Hong, Mei-Ren Wang, Yu-Ting Tseng, Po-Chun Liao, Min-Chuan Chung and 8 more

Abstract read
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In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Hsiao-Wen HuangDepartment of Chemistry, National Tsing Hua University, Hsinchu, 30013, Taiwan.
Yen-Hung LinInstitute of Biotechnology, National Tsing Hua University, Hsinchu, 30013, Taiwan.
Min-Hsuan LinDepartment of Medical Science and Institute of Bioinformatics and Structural Biology, National Tsing Hua University, Hsinchu, 30013, Taiwan.
Ya-Rong HuangInstitute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu, 30013, Taiwan.
Chih-Hung ChouInstitute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu, 30013, Taiwan.
Hsiao-Chin HongInstitute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu, 30013, Taiwan.
Mei-Ren WangDepartment of Chemistry, Chung Yuan Christian University, Taoyuan, 32023, Taiwan.
Yu-Ting TsengDepartment of Chemistry, Chung Yuan Christian University, Taoyuan, 32023, Taiwan.
Po-Chun LiaoDepartment of Chemistry, Chung Yuan Christian University, Taoyuan, 32023, Taiwan.
Min-Chuan ChungDepartment of Chemistry, Chung Yuan Christian University, Taoyuan, 32023, Taiwan.
Yu-Jie MaDepartment of Chemistry, Chung Yuan Christian University, Taoyuan, 32023, Taiwan.
Shou-Cheng WuDepartment of Biological Science and Technology, National Chiao Tung University, Hsinchu, 30013, Taiwan.
Yung-Jen ChuangDepartment of Medical Science and Institute of Bioinformatics and Structural Biology, National Tsing Hua University, Hsinchu, 30013, Taiwan. yjchuang@life.nthu.edu.tw.
Horng-Dar WangInstitute of Biotechnology, National Tsing Hua University, Hsinchu, 30013, Taiwan. hdwang@life.nthu.edu.tw.
Yun-Ming WangDepartment of Biological Science and Technology, National Chiao Tung University, Hsinchu, 30013, Taiwan. ymwang@mail.nctu.edu.tw.
Hsien-Da HuangInstitute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu, 30013, Taiwan. bryan@mail.nctu.edu.tw.
Tsai-Te LuDepartment of Chemistry, Chung Yuan Christian University, Taoyuan, 32023, Taiwan. TTLu@cycu.edu.tw.ORCID 0000-0001-6977-2568
Wen-Feng LiawDepartment of Chemistry, National Tsing Hua University, Hsinchu, 30013, Taiwan. wfliaw@mx.nthu.edu.tw.
National Yang Ming Chiao Tung University · TWChung Yuan Christian University · TWNational Tsing Hua University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ubiquitous and emerging physiology function of endogenous nitric oxide in vascular, myocardial, immune, and neuronal systems prompts chemists to develop a prodrug for the controlled delivery of ·NO in vivo and for the translational biomedical application. Inspired by the discovery of natural [Fe(NO)

Indexed as

LongevityAdenylate KinaseAnimalsCaenorhabditis elegansHalf-LifeIronKineticsMolecular StructureNitric OxideNitrogen OxidesSequence Analysis, RNASignal TransductionSpectrum AnalysisAdenylate Kinasedinitrosyl iron complexIronNitric OxideNitrogen OxidesAgingBioinorganic chemistryBiomedicineDrug deliveryNitric oxide

Identifiers

PMID29858679
OpenAlexW2807164512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.