Evidence map›Paper›PMID 29858614›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2018

Feasibility of dynamic stress

Sangwon Han, Young-Hak Kim, Jung-Min Ahn, Soo-Jin Kang, Jungsu S Oh, Eonwoo Shin, Changhwan Sung, Sun Young Chae, Seung-Jung Park, Gillan Grimberg and 2 more

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Diagnostic accuracy of dynamic CZT-SPECT in coronary artery disease. A systematic review and meta-analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Pooled it
  2. Review
  3. Article
  4. Article
  5. SPECT myocardial blood flow quantitation for the detection of angiographic stenoses with cardiac-dedicated CZT SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  6. All that glisters is not gold: the elusive difference between statistics and pathophysiology.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  7. Measuring myocardial blood flow using dynamic myocardial perfusion SPECT: artifacts and pitfalls.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. KSNM60 in Cardiology: Regrowth After a Long Pause.Nuclear medicine and molecular imaging · 2021
    Review
  12. Quantification of myocardial blood flow by CZT-SPECT with motion correction and comparison withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  13. Absolute myocardial blood flows derived by dynamic CZT scan vs invasive fractional flow reserve: Correlation and accuracy.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  14. The potential of regional myocardial blood flow measurement with SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  15. Myocardial blood flow assessment with SPECT systems: The renovation continues.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  16. Review
  17. Review
  18. Quantification of myocardial blood flow with dynamic SPECT acquisitions: ready for prime time?European journal of nuclear medicine and molecular imaging · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Sangwon HanDepartment of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Young-Hak KimDepartment of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Jung-Min AhnDepartment of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Soo-Jin KangDepartment of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Jungsu S OhDepartment of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Eonwoo ShinDepartment of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Changhwan SungDepartment of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Sun Young ChaeDepartment of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Seung-Jung ParkDepartment of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Gillan GrimbergGE Healthcare, Haifa, Israel.
Gil KovalskiGE Healthcare, Haifa, Israel.
Dae Hyuk MoonDepartment of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea. dhmoon@amc.seoul.kr.ORCID http://orcid.org/0000-0001-9892-4276

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe evaluated the feasibility of dynamic stress

methodsSubjects with stable known or suspected coronary artery disease (CAD) who had undergone or were scheduled to undergo fractional flow reserve (FFR) measurement were prospectively enrolled. Dynamic stress

resultsA total of 34 subjects were enrolled (25 men and 9 women; mean age 60.4 years). FFR was measured in 65 coronary arteries with intermediate lesions. The average global MPR was 2.58 ± 1.03. Global MPR was associated with the extent of CAD (P = 0.028) and global summed stress score (r = -0.60, P < 0.001). Regional MPR showed a significant correlation with diameter stenosis (r = -0.57, P < 0.001), minimum lumen diameter (r = 0.50, P < 0.001), summed stress score (r = -0.52, P < 0.001) and FFR (r = 0.52, P < 0.001). The area under the receiver operating characteristic curve of MPR for the diagnosis of functionally significant stenosis (FFR ≤0.8) was 0.79 (P < 0.001). The sensitivity and specificity of regional MPR were 67% and 83%, respectively, using a cut-off value of 2.0.

conclusionDynamic stress

Indexed as

Fractional Flow Reserve, MyocardialOrganophosphorus CompoundsOrganotechnetium CompoundsStress, PhysiologicalThallium RadioisotopesTomography, Emission-Computed, Single-PhotonCoronary Artery DiseaseFeasibility StudiesFemaleHumansMaleMiddle AgedOrganophosphorus CompoundsOrganotechnetium Compoundstechnetium tc-99m tetrofosminThallium-201Thallium RadioisotopesCadmium-zinc-tellurideFractional flow reserveMyocardial perfusion reserveSingle photon emission computed tomography

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.