Evidence map›Paper›PMID 29858588›Full record

ArticleProstate cancer and prostatic diseases2018

The association of lymph node dissection with 30-day perioperative morbidity among men undergoing minimally invasive radical prostatectomy: analysis of the National Surgical Quality Improvement Program (NSQIP).

Joseph Brito, Jorge Pereira, Daniel M Moreira, Gyan Pareek, Christopher Tucci, Ruiting Guo, Zheng Zhang, Ali Amin, Anthony Mega, Joseph Renzulli and 2 more

Abstract read
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In one paragraph

Article in Prostate cancer and prostatic diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. A systematic review and meta-analysis of unplanned hospital visits and re-admissions following radical prostatectomy for prostate cancer.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2021
    Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Joseph BritoWarren Alpert Medical School of Brown University, Providence, RI, USA.
Jorge PereiraWarren Alpert Medical School of Brown University, Providence, RI, USA.
Daniel M MoreiraDepartment of Urology, University of Illinois, Chicago, Illinois, USA.ORCID http://orcid.org/0000-0003-4517-244X
Gyan PareekWarren Alpert Medical School of Brown University, Providence, RI, USA.
Christopher TucciMinimally Invasive Urology Institute, The Miriam Hospital, Providence, RI, USA.
Ruiting GuoDepartment of Biostatistics, Brown University, Providence, RI, USA.
Zheng ZhangDepartment of Biostatistics, Brown University, Providence, RI, USA.
Ali AminDepartment of Pathology & Laboratory Medicine, The Miriam Hospital, Providence, RI, USA.
Anthony MegaDepartment of Hematology/Oncology, The Miriam Hospital, Providence, RI, USA.
Joseph RenzulliWarren Alpert Medical School of Brown University, Providence, RI, USA.
Dragan GolijaninWarren Alpert Medical School of Brown University, Providence, RI, USA.
Boris GershmanWarren Alpert Medical School of Brown University, Providence, RI, USA. Boris.Gershman@lifespan.org.ORCID http://orcid.org/0000-0001-5191-7255
Brown University · USProvidence College · USMiriam Hospital · USUniversity of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incremental morbidity of lymph node dissection (LND) among men undergoing radical prostatectomy remains uncertain. We therefore evaluated  the association of LND with perioperative morbidity among men undergoing minimally invasive radical prostatectomy (MIRP).

methodsWe identified 29,012 men aged 35-89 who underwent MIRP from 2010-2015 in the National Surgical Quality Improvement Program (NSQIP) database, of whom 47% underwent concomitant LND. The associations of LND with 30-day perioperative morbidity and mortality were evaluated using logistic regression, adjusted for patient features.

resultsMedian age at surgery was 63 (IQR 57, 67) years. There were statistically significant, but clinically insignificant, differences in several baseline characteristics stratified by performance of LND, including older age at surgery (p < 0.001), higher American Society of Anesthesiology (ASA) class (p < 0.001), and longer operative time (p < 0.001) for men who underwent LND. Overall, 30-day complications occurred in 4.3% of patients. There were no statistically significant differences in rates of 30-day complications (4.2 vs. 4.4%, p = 0.44), perioperative blood transfusion (1.7 vs. 1.7%, p = 0.99), hospital readmission (3.6 vs. 4.0%, p = 0.09), reoperation (1.1 vs. 1.1%, p = 0.80), or 30-day mortality (0.1 vs. 0.2%, p = 0.56) between patients who underwent MIRP alone or MIRP with LND, respectively. On multivariable analysis, LND was not significantly associated with an increased risk of perioperative morbidity or 30-day mortality.

conclusionsLND at the time of MIRP does not appear to be associated with an increased risk of perioperative morbidity.

Indexed as

Quality ImprovementAdultAgedAged, 80 and overFollow-Up StudiesHumansLength of StayLymph Node ExcisionMaleMiddle AgedMinimally Invasive Surgical ProceduresMorbidityOutcome Assessment, Health CarePerioperative PeriodPostoperative ComplicationsPrognosis

Identifiers

PMID29858588
OpenAlexW2806534234

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.