Evidence map›Paper›PMID 29858581›Full record

ArticleMucosal immunology2018

Influence of gut microbiome on mucosal immune activation and SHIV viral transmission in naive macaques.

Yongjun Sui, Amiran Dzutsev, David Venzon, Blake Frey, Vishal Thovarai, Giorgio Trinchieri, Jay A Berzofsky

Open access · bronzeAbstract read
In one paragraph

Article in Mucosal immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Anaerobe-Driven Inflammation and Epithelial Barrier Disruption in Genital HIV Acquisition.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Review
  3. Article
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  7. Review
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  12. Article
  13. Early treatment with anti-αFrontiers in immunology · 2022
    Article
  14. Article
  15. Review
  16. Article
  17. Microbiome Studies in Non-human Primates.Current HIV/AIDS reports · 2021
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yongjun SuiVaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA. suiy@mail.nih.gov.
Amiran DzutsevCancer and Inflammation Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
David VenzonBiostatistics and Data Management Section, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Blake FreyVaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Vishal ThovaraiCancer and Inflammation Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Giorgio TrinchieriCancer and Inflammation Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Jay A BerzofskyVaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA. berzofsj@mail.nih.gov.
National Institutes of Health · US

Funding

Role of mouse microbiome in cancer and inflammationZIABC011153 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI TRINCHIERI, GIORGIO · 2009 to 2025
$22.0M
Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

It is unknown whether the gut microbiome affects HIV transmission. In our recent SHIV vaccine study, we found that the naive rhesus macaques from two different sources had significantly different rates of infection against repeated low-dose intrarectal challenge with SHIV

Indexed as

AnimalsBacillotaBacteroidesCD4-Positive T-LymphocytesDisease SusceptibilityGastrointestinal MicrobiomeHIV-1HIV InfectionsHumansIntestinal MucosaKi-67 AntigenLymphocyte ActivationMacacaPrevotellaReceptors, CCR5RNA, Ribosomal, 16SKi-67 AntigenReceptors, CCR5RNA, Ribosomal, 16S

Identifiers

PMID29858581
PMCPMC6030500
OpenAlexW2806059811

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.