Evidence map›Paper›PMID 29858430›Full record

ReviewClinical medicine (London, England)2018

Hepatitis B virus reactivation in patients treated with immunosuppressive drugs: a practical guide for clinicians.

Apostolos Koffas, Grace E Dolman, Patrick Tf Kennedy

Open access · diamondAbstract readReview
In one paragraph

Review in Clinical medicine (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Guideline
  2. Pooled it
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  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Aftermath of COVID-19 and Critical Care in India.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021
    Article
  10. Review
  11. Article
  12. Review
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  15. Article
  16. Review
  17. [The expert consensus on clinical cure (functional cure) of chronic hepatitis B].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Apostolos KoffasGastroenterology Unit, University Hospital of Larisa, Thessaly, Greece.
Grace E DolmanBarts Liver Centre, Blizard Institute, Barts and the London School of Medicine and Dentistry, London, UK.
Patrick Tf KennedyBarts Liver Centre, Blizard Institute, Barts and the London School of Medicine and Dentistry, London, UK p.kennedy@qmul.ac.uk.
Queen Mary University of London · GBUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis B virus reactivation (HBVr) is emerging as an important clinical entity, with the advent of highly potent immunosuppression licensed for use as the treatment of a widening range of clinical indications. HBVr can lead to severe acute liver failure and death. Risk can be minimised through appropriate screening, monitoring and antiviral prophylaxis. Screening for serological markers at the -earliest opportunity is recommended. Risk stratification should then be performed on the basis of characteristics of the -underlying disease, markers of viral activity and the potency of proposed immunosuppression. In this review, we summarise the most recent recommendations from the relevant international societies. We also provide suggestions on how a robust multidisciplinary service can be delivered to prevent HBVr in UK clinical practice through optimisation of resources and introduction of checkpoints to prevent the inappropriate administration of immunosuppression to those at significant risk of HBVr.

Indexed as

Hepatitis B virusVirus ActivationAntiviral AgentsHepatitis B AntibodiesHepatitis B AntigensHepatitis B, ChronicHumansImmunosuppressive AgentsMass ScreeningPractice Guidelines as TopicUnited KingdomAntiviral AgentsHepatitis B AntibodiesHepatitis B AntigensImmunosuppressive AgentsChronic hepatitis Bimmunosuppressionreactivation

Identifiers

PMID29858430
PMCPMC6334086
OpenAlexW2805170695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.