ArticleClinical medicine (London, England)2018
Vitamin D: too much testing and treating?
Article in Clinical medicine (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Are There Ethnic Differences in Micronutrient Deficiencies in Preoperative Bariatric Patients? A Systematic Review and Meta-analysis.Obesity surgery · 2021Pooled it
- High-dose versus low-dose ergocalciferol for correcting hypovitaminosis D after fragility hip fracture: a randomized controlled trial.BMC geriatrics · 2021Trial
- Vitamin D supplementation has no effects on progression of motor dysfunction in amyotrophic lateral sclerosis (ALS).European journal of clinical nutrition · 2020Trial
- Vitamin D Activation and Mineral Ion Regulation.Advances in experimental medicine and biology · 2026Article
- Decoding Vitamin D Intake: How Much Is Too Much?Advances in experimental medicine and biology · 2026Review
- The impact of Choosing WiselyBMC health services research · 2025Article
- Voluntary vitamin D testing: a decade-long study of utilisation patterns and impact on deficiency outcomes in Taiwan.Public health nutrition · 2025Article
- Prevalence of Micronutrient Deficiencies in Preoperative Bariatric Patients in a New Zealand Tertiary Centre.Obesity surgery · 2024Article
- Review
- Machine learning-based prediction of vitamin D deficiency: NHANES 2001-2018.Frontiers in endocrinology · 2024Article
- Trends in diagnostic tests ordered for children: a retrospective analysis of 1.7 million laboratory test requests in Oxfordshire, UK from 2005 to 2019.Archives of disease in childhood · 2023Article
- Reduce unnecessary routine vitamin D testing.Canadian family physician Medecin de famille canadien · 2023Article
- Factors Associated with Potentially Inappropriate Screening for Vitamin D Deficiency among Women in Medically Underserved Regions of West Texas.Journal of clinical medicine · 2023Article
- Cost analysis of 25-hydroxy vitamin D tests in Turkiye with big data: A cross-sectional study.Northern clinics of Istanbul · 2023Article
- Health, financial and environmental impacts of unnecessary vitamin D testing: a triple bottom line assessment adapted for healthcare.BMJ open · 2022Review
- An analysis of the vitamin D overtesting in a tertiary healthcare centre.Biochemia medica · 2022Article
- Vitamin D: a 14-year retrospective study at a clinical laboratory in Brazil.Archives of endocrinology and metabolism · 2022Article
- Effects of Routine Health Care Combined with Oral Vitamin D on Linear Growth in 5-Year-Old Children.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Laboratory Test Utilization Practices in Hamad Medical Corporation; Role of Laboratory Supervisors and Clinicians in Improper Test Utilization; a Descriptive Pilot Study.Journal of multidisciplinary healthcare · 2022Article
- Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation.Nutrients · 2021Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is clinical uncertainty as to the testing of serum 25--Hydroxy vitamin D (25[OH]D) concentrations and when to use high-dose supplementation. Data show that there has been a rapid increase in the number of tests performed within the Northumbria Healthcare NHS Foundation Trust over the past 8 years and an increase in high-dose supplementation over the past 5 years. We performed a retrospective analysis of the 25(OH)D test requests over the period from January to -October 2017. A total of 17,405 tests were performed in this time period. The overall average concentration was 57.5 nmol/L and this figure was similar across age groups, although a larger proportion of patients aged over 75 had a concentration <25 nmol/L. Test requests were classified into 'appropriate', 'inappropriate' and 'uncertain' categories based on current expert opinion. We found that between 70.4% and 77.5% of tests could be inappropriate, depending on whether the 'uncertain' categories of falls and osteoporosis are considered to be justified. Tiredness, fatigue or exhaustion was the reason for testing in 22.4% of requests. We suggest that a more rational approach to testing, and subsequent treating, could lead to reductions in costs to the healthcare system and patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.