Evidence map›Paper›PMID 29858370›Full record

ArticleJournal of the American Heart Association2018

Stroke in Adults With Coarctation of the Aorta: A National Population-Based Study.

Sarah S Pickard, Kimberlee Gauvreau, Michelle Gurvitz, Joshua J Gagne, Alexander R Opotowsky, Kathy J Jenkins, Ashwin Prakash

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 66 citations in OpenAlex.

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  14. Coarctation of the Aorta: Diagnosis and Management.Diagnostics (Basel, Switzerland) · 2023
    Review
  15. Comparison of aortic stiffness and hypertension in repaired coarctation patients with a bicuspid versus a tricuspid aortic valve.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  16. Relationship between left atrial myopathy and atrial fibrillation in adults with coarctation of aorta.American heart journal plus : cardiology research and practice · 2023
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sarah S PickardDepartment of Cardiology, Boston Children's Hospital, Boston, MA.
Kimberlee GauvreauDepartment of Cardiology, Boston Children's Hospital, Boston, MA.
Michelle GurvitzDepartment of Cardiology, Boston Children's Hospital, Boston, MA.
Joshua J GagneDivision of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Alexander R OpotowskyDepartment of Cardiology, Boston Children's Hospital, Boston, MA.
Kathy J JenkinsDepartment of Cardiology, Boston Children's Hospital, Boston, MA.
Ashwin PrakashDepartment of Cardiology, Boston Children's Hospital, Boston, MA ashwin.prakash@cardio.chboston.org.
Boston Children's Hospital · USHarvard University · USBrigham and Women's Hospital · US

Funding

RESEARCH METHODS IN PEDIATRICS HEART DISEASET32HL007572 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI Sarah D DE FERRANTI, Jane W. Newburger · 1985 to 2026
$13.0M
NHLBI NIH HHS T32 HL007572
6 · The paper itself

Abstract

backgroundAdults with repaired coarctation of the aorta (CoA) have reduced long-term survival compared with the general population. This study aimed to determine whether CoA is independently associated with premature ischemic and hemorrhagic stroke in the contemporary era. METHODS AND

resultsThis was a cross-sectional study utilizing the National Inpatient Sample database from 2005 to 2014. We hypothesized that patients with CoA are hospitalized with ischemic and hemorrhagic stroke at a younger age compared with the general population. To test this hypothesis, we compared the age at stroke in patients with and without a diagnosis of CoA using simple and multivariable weighted linear regression. Among 4 894 582 stroke discharges, 207 had a diagnosis of CoA. Patients with CoA had strokes at significantly younger age compared with patients without CoA: 18.9 years younger for all-cause stroke (

conclusionsPatients with CoA have both ischemic and hemorrhagic strokes at significantly younger ages compared with the general population.

Indexed as

Population SurveillanceAdultAgedAged, 80 and overAge FactorsAortic CoarctationCross-Sectional StudiesDatabases, FactualFemaleHumansIncidenceIntracranial AneurysmMaleMiddle AgedPrevalenceRetrospective Studiesadult congenital heart diseasecoarctation of the aortaintracranial aneurysmstroke

Identifiers

PMID29858370
PMCPMC6015389
OpenAlexW2806901414

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.