Evidence map›Paper›PMID 29858367›Full record

ArticleJournal of the American Heart Association2018

Longitudinal Changes in Cholesterol Efflux Capacities in Patients With Coronary Artery Disease Undergoing Lifestyle Modification Therapy.

Marjorie Boyer, Valérie Lévesque, Paul Poirier, André Marette, Patricia L Mitchell, Samia Mora, Patrick Mathieu, Jean-Pierre Després, Éric Larose, Benoit J Arsenault

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Marjorie BoyerCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Canada.
Valérie LévesqueCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Canada.
Paul PoirierCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Canada.
André MaretteCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Canada.
Patricia L MitchellCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Canada.
Samia MoraCenter for Lipid Metabolomics, Divisions of Preventive and Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Patrick MathieuCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Canada.
Jean-Pierre DesprésCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Canada.
Éric LaroseCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Canada.
Benoit J ArsenaultCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Canada benoit.arsenault@criucpq.ulaval.ca.
Université Laval · CAInstitut Universitaire de Cardiologie et de Pneumologie de Québec · CABrigham and Women's Hospital · US

Funding

Total plasma and IgG glycomes, statin therapy and ASCVD eventsR01HL117861 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MORA, SAMIA · 2013 to 2022
$3.8M
Reducing Inflammation for the Prevention of CVD: A Focus on Eicosanoid PathwaysR01HL134811 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MORA, SAMIA · 2017 to 2020
$3.0M
Circulating plasma metabolites, diet, and risk of type 2 diabetesR01DK112940 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI HU, FRANK B, MORA, SAMIA · 2018 to 2021
$2.9M
CIHR 161971NHLBI NIH HHS R01 HL117861NHLBI NIH HHS R01 HL134811NIDDK NIH HHS R01 DK112940
6 · The paper itself

Abstract

backgroundOur objective was to identify the determinants of high-density lipoprotein cholesterol efflux capacity (HDL-CEC) changes in patients with coronary artery disease who participated in a lifestyle modification program aimed at increasing physical activity levels and improving diet quality. METHODS AND

resultsA total of 86 men with coronary artery disease aged between 35 and 80 years participated in a 1-year lifestyle modification program that aimed to achieve a minimum of 150 minutes of aerobic physical activity weekly and improve diet quality. HDL-CECs were measured before and after the 1-year intervention using

conclusionsResults of this study suggest that increases in high-density lipoprotein cholesterol and apolipoprotein AI levels typically observed in patients with coronary artery disease undergoing healthy lifestyle modification therapy may be indicative of higher plasma concentrations of functional high-density lipoprotein particles.

Indexed as

Life StyleAdultAgedAged, 80 and overBiomarkersCaloric RestrictionCardiorespiratory FitnessCholesterol, HDLCholesterol, LDLCoronary Artery DiseaseDiet, HealthyFollow-Up StudiesHumansMaleMiddle AgedTime FactorsBiomarkersCholesterol, HDLCholesterol, LDLadipose tissuecholestrol efflux capacitycoronary artery diseaselifestylelipids and lipoproteins

Identifiers

PMID29858367
PMCPMC6015361
OpenAlexW2807669703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.