Evidence map›Paper›PMID 29858281›Full record

ArticleJournal of the American Society of Nephrology : JASN2018

C5b9 Formation on Endothelial Cells Reflects Complement Defects among Patients with Renal Thrombotic Microangiopathy and Severe Hypertension.

Sjoerd A M E G Timmermans, Myrurgia A Abdul-Hamid, Judith Potjewijd, Ruud O M F I H Theunissen, Jan G M C Damoiseaux, Chris P Reutelingsperger, Pieter van Paassen, Limburg Renal Registry

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 96 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Complement activation in secondary thrombotic microangiopathies.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Review
  6. Observational
  7. Review
  8. Article
  9. Article
  10. Proteasome inhibitor-associated thrombotic microangiopathy: a real-world retrospective and pharmacovigilance database analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Kidney international reports · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sjoerd A M E G TimmermansDepartments of Nephrology and Clinical Immunology and.
Myrurgia A Abdul-HamidPathology and.
Judith PotjewijdDepartments of Nephrology and Clinical Immunology and.
Ruud O M F I H TheunissenDepartments of Nephrology and Clinical Immunology and.
Jan G M C DamoiseauxCentral Diagnostic Laboratory, Maastricht University Medical Center, Maastricht, The Netherlands; and.
Chris P ReutelingspergerDepartment of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.
Pieter van PaassenDepartments of Nephrology and Clinical Immunology and p.vanpaassen@maastrichtuniversity.nl.
Limburg Renal Registry
Maastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAntibodies, Monoclonal, HumanizedCase-Control StudiesCells, CulturedComorbidityComplement ActivationComplement Membrane Attack ComplexComplement System ProteinsDisease ProgressionEndothelial CellsFemaleHumansHypertensionKidney DiseasesKidney Failure, ChronicAntibodies, Monoclonal, HumanizedComplement Membrane Attack ComplexComplement System Proteinseculizumabcomplementhemolytic uremic syndromehypertensionrenal biopsy

Identifiers

PMID29858281
PMCPMC6065094
OpenAlexW2806742338

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.