Evidence map›Paper›PMID 29858246›Full record

ArticleThe Journal of biological chemistry2018

β

Pei-Yin Ho, Hui Li, Tengis S Pavlov, Roland D Tuerk, Diego Tabares, René Brunisholz, Dietbert Neumann, Alexander Staruschenko, Kenneth R Hallows

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Regulation of the intestinal NaAmerican journal of physiology. Cell physiology · 2024
    Article
  5. Article
  6. Article
  7. Metformin Inhibits NaFrontiers in physiology · 2022
    Article
  8. Review
  9. AMPK phosphorylation of the βAmerican journal of physiology. Renal physiology · 2019
    Article
  10. Article
  11. AMPK-Mediated Regulation of Alpha-Arrestins and Protein Trafficking.International journal of molecular sciences · 2019
    Review
  12. AMP-Activated Protein Kinase (AMPK)-Dependent Regulation of Renal Transport.International journal of molecular sciences · 2018
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Pei-Yin HoDivision of Nephrology and Hypertension, Department of Medicine and USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033.
Hui LiDivision of Nephrology and Hypertension, Department of Medicine and USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033.
Tengis S Pavlovthe Division of Hypertension and Vascular Research, Henry Ford Health System, Detroit, Michigan 48202; Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226.
Roland D TuerkDepartment of Biology, Institute of Cell Biology, ETH Zurich, 8093 Zurich, Switzerland.
Diego TabaresDivision of Nephrology and Hypertension, Department of Medicine and USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033.
René BrunisholzFunctional Genomics Center, ETH Zurich, 8097 Zurich, Switzerland.
Dietbert NeumannDepartment of Biology, Institute of Cell Biology, ETH Zurich, 8093 Zurich, Switzerland; Department of Pathology, School for Cardiovascular Diseases, Maastricht University, 6200 MD Maastricht, The Netherlands.
Alexander StaruschenkoDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226.
Kenneth R HallowsDivision of Nephrology and Hypertension, Department of Medicine and USC/UKRO Kidney Research Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033. Electronic address: hallows@usc.edu.
University of Southern California · USETH Zurich · CHHenry Ford Health System · USMaastricht University · NLMedical College of Wisconsin · US

Funding

Renal ion channels in the control of blood pressureR35HL135749 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI STARUSCHENKO, ALEXANDER · 2017 to 2023
$3.6M
Mechanisms and Relevance of Sodium Transport Regulation by AMPKR01DK075048 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HALLOWS, KENNETH R · 2007 to 2015
$2.5M
Mechanisms and relevance of ENaC regulation by EGF and Rac1R01HL108880 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI STARUSCHENKO, ALEXANDER · 2012 to 2016
$1.9M
Regulation of ENaC in salt-sensitive hypertension via inflammation-induced ROS productionR00HL116603 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI PAVLOV, TENGIS S · 2015 to 2017
$716k
Regulation of ENaC in salt-sensitive hypertension via inflammation-induced ROS prK99HL116603 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI PAVLOV, TENGIS S · 2013 to 2014
$180k
NHLBI NIH HHS K99 HL116603NHLBI NIH HHS R00 HL116603NHLBI NIH HHS R01 HL108880NHLBI NIH HHS R35 HL135749NIDDK NIH HHS R01 DK075048
6 · The paper itself

Abstract

Our previous work has established that the metabolic sensor AMP-activated protein kinase (AMPK) inhibits the epithelial Na

Indexed as

14-3-3 ProteinsAMP-Activated Protein KinasesAnimalsCell LineCHO CellsCricetulusEpithelial CellsEpithelial Sodium ChannelsHEK293 CellsHumansKidney Tubules, CollectingMiceNedd4 Ubiquitin Protein LigasesPhosphorylationRho Guanine Nucleotide Exchange Factors14-3-3 ProteinsAMP-Activated Protein KinasesEpithelial Sodium ChannelsNedd4l protein, mouseNedd4 Ubiquitin Protein LigasesRho Guanine Nucleotide Exchange Factors14-3-3 proteinAMP-activated kinase (AMPK)epithelial sodium channel (ENaC)kidneysodium transportubiquitin ligaseβ-Pix

Identifiers

PMID29858246
PMCPMC6065188
OpenAlexW2805718179

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.