ArticleNutrition, metabolism, and cardiovascular diseases : NMCD2018
A longitudinal study of altered taste and smell perception and change in blood pressure.
Article in Nutrition, metabolism, and cardiovascular diseases : NMCD, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- The Prevalence of Olfactory Dysfunction in the General Population: A Systematic Review and Meta-analysis.American journal of rhinology & allergy · 2021Pooled it
- Onset and duration of symptoms of loss of smell/taste in patients with COVID-19: A systematic review.American journal of otolaryngologyPooled it
- Epidemiology of olfactory dysfunction in China: a nationwide population-based cross-sectional study.Annals of medicine · 2026Article
- Insights into the interplay between stroke and depression through lipid metabolism-related diagnostic genes.Molecular brain · 2026Article
- Longitudinal Association of Olfactory Function with Frailty in Older Adults: The Atherosclerosis Risk in Communities Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Human exposure to aerosol from indoor gas stove cooking and the resulting cardiovascular system responses.Toxicology reports · 2024Article
- Sleep disorders as independent predictors of taste dysfunction risk.BMC oral health · 2024Article
- Oral conditions are associated with salt taste disability among American adults.Oral diseases · 2024Article
- Association between olfactory function and metabolic syndrome in bipolar disorder patients: a cross-sectional study.BMC psychiatry · 2024Article
- Genome-wide association analysis of hypertension and epigenetic aging reveals shared genetic architecture and identifies novel risk loci.Scientific reports · 2024Article
- Article
- Olfactory function in diabetes mellitus.Journal of clinical & translational endocrinology · 2024Review
- Hypertension facilitates age-related diseases. ~ Is hypertension associated with a wide variety of diseases?~.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Review
- Article
- Article
- Olfactory loss is a predisposing factor for depression, while olfactory enrichment is an effective treatment for depression.Frontiers in neuroscience · 2022Article
- Not Only COVID-19: Involvement of Multiple Chemosensory Systems in Human Diseases.Frontiers in neural circuits · 2022Review
- No ambiguity: Chemosensory-based ayurvedic classification of medicinal plants can be fingerprinted using E-tongue coupled with multivariate statistical analysis.Frontiers in pharmacology · 2022Article
- Are Multiple Chemosensory Systems Accountable for COVID-19 Outcome?Journal of clinical medicine · 2021Review
- NIH Workshop Report: sensory nutrition and disease.The American journal of clinical nutrition · 2021Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
BACKGROUND AND
aimsPrevious studies suggest that olfactory receptors, which mediate smell chemosensation, are located in the kidney and involved in blood pressure regulation. Mammalian epithelial sodium channels located in taste receptor cells are also found to participate in blood pressure regulation. However, there is currently no human study that has examined the association between taste and smell function and blood pressure. We thus conducted a longitudinal study to examine whether participants with altered taste and smell perception had larger increases in blood pressure compared with those without altered perception in a community-based cohort. METHODS AND
resultsThe study included 5190 Chinese adults (4058 men and 1132 women) who were normotensive at baseline. Taste and smell perception were assessed via questionnaire in 2012 (baseline). Blood pressure was measured in 2012 and 2014 to determine relative change in blood pressure. Mean differences of 2-year blood pressure change and 95% confidence intervals (CIs) across four categories of taste and smell perception were calculated after adjusting for known risk factors for hypertension. After adjusting for potential confounders, individuals with altered taste and smell perception had larger increases in systolic blood pressure (adjusted mean difference = 5.1 mmHg, 95% CI: 0.1-10.0, p-value: 0.04) and mean arterial pressure (adjusted mean difference = 3.8 mmHg, 95% CI: 0.4-7.1, p-value: 0.03) after two years of follow-up compared with those having neither altered taste nor altered smell perception. No significant association was observed in individuals with altered taste or smell perception only.
conclusionOur results suggest an association between chemosensory function and blood pressure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.