Evidence map›Paper›PMID 29857565›Full record

Trial reportToxins2018

Monocentric Prospective Study into the Sustained Effect of Incobotulinumtoxin A (XEOMIN

Ioana Ion, Dimitri Renard, Anne Le Floch, Marie De Verdal, Stephane Bouly, Anne Wacongne, Alessandro Lozza, Giovanni Castelnovo

Registry-linked trialOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in Toxins, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05598723 (A Randomized, Double-Blind Study on the Effect of OnabotulinumtoxinA), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05598723 phase3recruitingnot on this mapstarted 2023, after this paper: background citation

A Randomized, Double-Blind Study on the Effect of OnabotulinumtoxinA (BOTOX®) vs. IncobotulinumtoxinA (XEOMIN®) Botulinum Toxin in Adults With Chronic Migraine

TypeinterventionalSponsorNaval Medical Center Camp LejeuneRan2023 to 2027Enrolled128ConditionsChronic MigraineArmsIncobotulinumtoxinA (XEOMIN®), OnabotulinumtoxinA (BOTOX®)
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. A novel technique of botulinum toxin injection around skull sutures for chronic migraine: A randomized controlled clinical trial.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Ioana IonDepartment of Neurology, Nimes University Hospital, 30900 Nimes, France. IOANAMARIA.ION@chu-nimes.fr.
Dimitri RenardDepartment of Neurology, Nimes University Hospital, 30900 Nimes, France. dimitri.RENARD@chu-nimes.fr.
Anne Le FlochDepartment of Neurology, Nimes University Hospital, 30900 Nimes, France. anne.LEFLOCH@chu-nimes.fr.
Marie De VerdalDepartment of Neurology, Nimes University Hospital, 30900 Nimes, France. marie.DEVERDAL@chu-nimes.fr.
Stephane BoulyDepartment of Neurology, Nimes University Hospital, 30900 Nimes, France. stephane.BOULY@chu-nimes.fr.
Anne WacongneDepartment of Neurology, Nimes University Hospital, 30900 Nimes, France. anne.WACONGNE@chu-nimes.fr.
Alessandro LozzaNeurological Institute, Foundation Casimiro Mondino, 27100 Pavia, Italy. alessandro.lozza@mondino.it.
Giovanni CastelnovoDepartment of Neurology, Nimes University Hospital, 30900 Nimes, France. giovanni.castelnovo@chu-nimes.fr.
Université de Nîmes · FRFondazione Istituto Neurologico Nazionale Casimiro Mondino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Refractory chronic migraine is a disabling disorder impacting quality of life. BOTOX

Indexed as

AdultAgedBotulinum Toxins, Type AFemaleHumansInjectionsMaleMiddle AgedMigraine DisordersNeuromuscular AgentsTreatment OutcomeYoung AdultBotulinum Toxins, Type AincobotulinumtoxinANeuromuscular Agentsmedication overuse headacheprophylactic treatmentrefractory chronic migrainetension headacheXEOMIN®

Identifiers

PMID29857565
PMCPMC6024863
OpenAlexW2806780607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.