ArticleMaterials (Basel, Switzerland)2018
Exploring the Potential of Electrical Impedance Tomography for Tissue Engineering Applications.
Article in Materials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Review
- Evaluation of Cancer Cell Lines by Four-Point Probe Technique, by Impedance Measurements in Various Frequencies.Biosensors · 2021Article
- Recent Advances in Monitoring Cell Behavior Using Cell-Based Impedance Spectroscopy.Micromachines · 2020Review
- Application of Impedance-Based Techniques in Hepatology Research.Journal of clinical medicine · 2019Review
- Applications of Bioimpedance Measurement Techniques in Tissue Engineering.Journal of electrical bioimpedance · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In tissue engineering, cells are generally cultured in biomaterials to generate three-dimensional artificial tissues to repair or replace damaged parts and re-establish normal functions of the body. Characterizing cell growth and viability in these bioscaffolds is challenging, and is currently achieved by destructive end-point biological assays. In this study, we explore the potential to use electrical impedance tomography (EIT) as a label-free and non-destructive technology to assess cell growth and viability. The key challenge in the tissue engineering application is to detect the small change of conductivity associated with sparse cell distributions in regards to the size of the hosting scaffold, i.e., low volume fraction, until they assemble into a larger tissue-like structure. We show proof-of-principle data, measure cells within both a hydrogel and a microporous scaffold with an ad-hoc EIT equipment, and introduce the frequency difference technique to improve the reconstruction.
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Registered trials
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