Evidence map›Paper›PMID 29857512›Full record

ArticleInternational journal of molecular sciences2018

Downregulations of AKT/mTOR Signaling Pathway for

Yu-Tzu Tsao, Chun-Yu Kuo, Shun-Ping Cheng, Che-Hsin Lee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Journal of Cancer · 2024
    Article
  5. Review
  6. Review
  7. Review
  8. Acta biochimica et biophysica Sinica · 2023
    Review
  9. Frontiers in cellular and infection microbiology · 2023
    Review
  10. Review
  11. Pharmaceutics · 2022
    Review
  12. Recombinant AttenuatedCancers · 2022
    Review
  13. Article
  14. Integration ofCancers · 2021
    Review
  15. International journal of medical sciences · 2021
    Article
  16. International journal of medical sciences · 2021
    Article
  17. Racially Disparate Expression of mTOR/ERK-1/2 Allied Proteins in Cancer.Frontiers in cell and developmental biology · 2021
    Review
  18. Perspectives on OncolyticFrontiers in immunology · 2021
    Review
  19. Article
  20. The extracts ofInternational journal of medical sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Yu-Tzu TsaoDivision of Nephrology, Department of Medicine, Taoyuan General Hospital, Taoyuan 330, Taiwan. tsaoyutzu@gmail.com.
Chun-Yu KuoGraduate Institute of Basic Medical Science, School of Medicine, China Medical University, Taichung 404, Taiwan. jay999kimo@yahoo.com.tw.
Shun-Ping ChengDepartment of Physical Medicine and Rehabilitation, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan 330, Taiwan. tsaoyt@mail.tygh.gov.tw.
Che-Hsin LeeDepartment of Biological Sciences, National Sun Yat-sen University, Kaohsiung 804, Taiwan. chlee@mail.nsysu.edu.tw.ORCID 0000-0002-8543-3862
China Medical University · TWMinistry of Health and Welfare · TWNational Sun Yat-sen University · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The roles of Matrix MetalloProteinases (MMPs), such as MMP-9, in tumor metastasis are well studied, and this in turns stimulates the development of MMP inhibitors as antitumor agents. Previously,

Indexed as

Gene Expression RegulationSignal TransductionAnimalsCell Line, TumorCell MovementDisease Models, AnimalHumansMatrix Metalloproteinase 9MiceNeoplasm MetastasisNeoplasmsPhosphorylationProto-Oncogene Proteins c-aktSalmonellaTOR Serine-Threonine KinasesXenograft Model Antitumor AssaysMatrix Metalloproteinase 9Proto-Oncogene Proteins c-aktTOR Serine-Threonine Kinasesmatrix metalloproteinasesmetastasisSalmonellatumor-targeting

Identifiers

PMID29857512
PMCPMC6032045
OpenAlexW2806245406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.