Evidence map›Paper›PMID 29857470›Full record

ArticleNutrients2018

Impaired Gastric Myoelectrical Reactivity in Children and Adolescents with Obesity Compared to Normal-Weight Controls.

Katja Weimer, Helene Sauer, Bjoern Horing, Francesco Valitutti, Nazar Mazurak, Stephan Zipfel, Andreas Stengel, Paul Enck, Isabelle Mack

Abstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Food intake and eating behaviour during a real-life Snack Scenario in childhood obesity-An experiment using a hidden camera.European eating disorders review : the journal of the Eating Disorders Association · 2025
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katja WeimerClinic for Psychosomatic Medicine and Psychotherapy, University Hospital Ulm, 89081 Ulm, Germany. katja.weimer@uni-ulm.de.ORCID 0000-0001-8656-607X
Helene SauerDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Hospital Tübingen, 72076 Tübingen, Germany. helene.sauer@medizin.uni-tuebingen.de.
Bjoern HoringInstitute of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany. b.horing@uke.de.
Francesco ValituttiPediatric Gastroenterology and Liver Unit, Department of Pediatrics, Sapienza University of Rome, 00161 Rome, Italy. francesco.valitutti@uniroma1.it.ORCID 0000-0002-1473-2240
Nazar MazurakDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Hospital Tübingen, 72076 Tübingen, Germany. nazar.mazurak@med.uni-tuebingen.de.
Stephan ZipfelDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Hospital Tübingen, 72076 Tübingen, Germany. stephan.zipfel@med.uni-tuebingen.de.
Andreas StengelDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Hospital Tübingen, 72076 Tübingen, Germany. andreas.stengel@med.uni-tuebingen.de.
Paul EnckDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Hospital Tübingen, 72076 Tübingen, Germany. paul.enck@uni-tuebingen.de.ORCID 0000-0001-8873-0486
Isabelle MackDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Hospital Tübingen, 72076 Tübingen, Germany. isabelle.mack@uni-tuebingen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity often has its onset in childhood and can be accompanied by various comorbidities such as functional gastrointestinal disorders and altered gastric myoelectrical activity (GMA). This study investigates whether obesity in childhood and adolescence is already associated with altered GMA, and whether an inpatient weight loss program affects GMA. Sixty children with obesity (OBE) and 27 normal-weight children (NW) (12.9 ± 1.7 years; 51% female) were compared for their GMA at rest, after a stress test, and after a drink-to-full water load test. A continuous electrogastrogram (EGG) was recorded and analyzed with respect to gastric slow waves and tachygastric activity. OBE were examined upon admission (T1) and before discharge (T2) following an inpatient weight loss program; NW served as control group. Compared to NW, children with obesity showed flattened GMA as indicated by lower tachygastric reactivity after stress and water load test at T1. Data of OBE did not differ between T1 and T2. EGG parameters were associated neither with sex, age, and BMI nor with subjective stress and food intake. Children with obesity show impaired gastric myoelectrical reactivity in response to a stress and water load test compared to normal-weight controls, which does not change during an inpatient weight loss program.

Indexed as

Weight Reduction ProgramsAdolescentBody Mass IndexChildChild Nutritional Physiological PhenomenaComorbidityEarly DiagnosisElectromyographyEnteric Nervous SystemFemaleGastric MucosaGastrointestinal DiseasesGermanyHumansMaleOverweightautonomic nervous systembrain-gut axisgastric myoelectrical reactivityobesitypsychosomaticstress

Identifiers

PMID29857470
PMCPMC6024785

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.