ArticlePloS one2018
A scoping review of biopsychosocial risk factors and co-morbidities for common spinal disorders.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 3 of them syntheses that pooled it.
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The trial behind it
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Who cites it
49 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Is there an association between diabetes and neck and back pain? An updated systematic review with meta-analyses.Chiropractic & manual therapies · 2026Pooled it
- What do we know about flares in spinal and pelvic girdle pain? A scoping review.BMC musculoskeletal disorders · 2026Pooled it
- The association between psychosocial factors and mental health symptoms in cervical spine pain with or without radiculopathy on health outcomes: a systematic review.BMC musculoskeletal disorders · 2023Pooled it
- Effects of high- versus moderate-intensity multimodal whole-body training to improve inspiratory muscle function in persons with chronic nonspecific low back pain.BMC sports science, medicine & rehabilitation · 2026Article
- A population-based survey of beliefs about neck pain and its associated disorders: a cross-sectional study.BMC musculoskeletal disorders · 2025Article
- Understanding the Comorbidities Among Psychiatric Disorders, Chronic Low Back Pain, and Spinal Degenerative Disease Using Observational and Genetically Informed Analyses.Biological psychiatry global open science · 2025Article
- Untangling the association between the burden of chronic back problems, current utilization of chiropractic care, and availability of chiropractors at the health region level: an ecological study protocol.The Journal of the Canadian Chiropractic Association · 2025Article
- Deep Learning-Based Prediction Model for Gait Recovery after a Spinal Cord Injury.Diagnostics (Basel, Switzerland) · 2024Article
- Ventricular-subventricular zone stem cell niche adaptations in a mouse model of post-infectious hydrocephalus.Frontiers in neuroscience · 2024Article
- Association between spinal and non-spinal health conditions reported in epidemiological studies: a scoping review protocol.BMJ open · 2023Article
- Clinical indicators for recommending continued care to patients with neck pain in chiropractic practice: a cohort study.Chiropractic & manual therapies · 2023Observational
- Spinal Pain, Chronic Health Conditions and Health Behaviors: Data from the 2016-2018 National Health Interview Survey.International journal of environmental research and public health · 2023Article
- Multi-domain biopsychosocial postoperative recovery trajectories associate with patient outcomes following lumbar fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- Application of platelet-rich plasma in spinal surgery.Frontiers in endocrinology · 2023Review
- The John A. Sweaney Lecture: Virtual, September 2021, Given by Dr Michele Maiers. A Time to Lead: Reflections During a Pandemic.Journal of chiropractic humanities · 2022Article
- The prevalence of suicide prevention training and suicide-related terminology in United States chiropractic training and licensing requirements.The Journal of chiropractic education · 2022Article
- Influence of a Sacroiliac Belt on Pain and Functional Impairment in Patients With Low Back Pain: A Randomized Trial.Journal of chiropractic medicine · 2022Article
- Evaluating a novel, low-cost technique for cervical-spine immobilization for application in resource-limited LMICs: a non-inferiority trial.Spinal cord · 2022Article
- Vertebral Related Diseases in Healthcare: The Role of Pain Management and Rehabilitation.Healthcare (Basel, Switzerland) · 2022Article
- Beliefs about back pain and associations with clinical outcomes: a primary care cohort study.BMJ open · 2022Observational
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this review was to identify risk factors, prognostic factors, and comorbidities associated with common spinal disorders.
methodsA scoping review of the literature of common spinal disorders was performed through September 2016. To identify search terms, we developed 3 terminology groups for case definitions: 1) spinal pain of unknown origin, 2) spinal syndromes, and 3) spinal pathology. We used a comprehensive strategy to search PubMed for meta-analyses and systematic reviews of case-control studies, cohort studies, and randomized controlled trials for risk and prognostic factors and cross-sectional studies describing associations and comorbidities.
resultsOf 3,453 candidate papers, 145 met study criteria and were included in this review. Risk factors were reported for group 1: non-specific low back pain (smoking, overweight/obesity, negative recovery expectations), non-specific neck pain (high job demands, monotonous work); group 2: degenerative spinal disease (workers' compensation claim, degenerative scoliosis), and group 3: spinal tuberculosis (age, imprisonment, previous history of tuberculosis), spinal cord injury (age, accidental injury), vertebral fracture from osteoporosis (type 1 diabetes, certain medications, smoking), and neural tube defects (folic acid deficit, anti-convulsant medications, chlorine, influenza, maternal obesity). A range of comorbidities was identified for spinal disorders.
conclusionMany associated factors for common spinal disorders identified in this study are modifiable. The most common spinal disorders are co-morbid with general health conditions, but there is a lack of clarity in the literature differentiating which conditions are merely comorbid versus ones that are risk factors. Modifiable risk factors present opportunities for policy, research, and public health prevention efforts on both the individual patient and community levels. Further research into prevention interventions for spinal disorders is needed to address this gap in the literature.
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