Evidence map›Paper›PMID 29856641›Full record

ArticleOrganic letters2018

Visible Light-Mediated Decarboxylative Alkylation of Pharmaceutically Relevant Heterocycles.

Alexandra C Sun, Edward J McClain, Joel W Beatty, Corey R J Stephenson

Abstract read
In one paragraph

Article in Organic letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Chemical science · 2026
    Article
  2. An Oxygen Walk Approach for C3 Selective Hydroxylation of Pyridines.Synlett : accounts and rapid communications in synthetic organic chemistry · 2025
    Article
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  13. Article
  14. Illuminating Photoredox Catalysis.Trends in chemistry · 2019
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alexandra C SunWillard Henry Dow Laboratory, Department of Chemistry , University of Michigan , 930 North University Avenue , Ann Arbor , Michigan 48109 , United States.
Edward J McClainWillard Henry Dow Laboratory, Department of Chemistry , University of Michigan , 930 North University Avenue , Ann Arbor , Michigan 48109 , United States.
Joel W BeattyWillard Henry Dow Laboratory, Department of Chemistry , University of Michigan , 930 North University Avenue , Ann Arbor , Michigan 48109 , United States.
Corey R J StephensonWillard Henry Dow Laboratory, Department of Chemistry , University of Michigan , 930 North University Avenue , Ann Arbor , Michigan 48109 , United States.ORCID 0000-0002-2443-5514

Funding

Photoredox Catalysis Applications to Bioactive CompoundsR01GM096129 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI STEPHENSON, COREY · 2011 to 2015
$1.5M
NIGMS NIH HHS R01 GM096129
6 · The paper itself

Abstract

A net redox-neutral method for the decarboxylative alkylation of heteroarenes using photoredox catalysis is reported. Additionally, this method features the use of simple, commercially available carboxylic acid derivatives as alkylating agents, enabling the facile alkylation of a variety of biologically relevant heterocyclic scaffolds under mild conditions.

Indexed as

LightAlkylationCatalysisMolecular StructureOxidation-Reduction

Identifiers

PMID29856641
PMCPMC6014829

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.