Evidence map›Paper›PMID 29856288›Full record

Trial reportThe International journal of clinical and experimental hypnosis

KETAMINE AS A POSSIBLE MODERATOR OF HYPNOTIZABILITY: A FEASIBILITY STUDY.

David R Patterson, Christine Hoffer, Mark P Jensen, Shelley A Wiechman, Sam R Sharar

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The International journal of clinical and experimental hypnosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Do psychedelics change beliefs?Psychopharmacology · 2022
    Review
  4. Inducing Effects of Illegal Drugs to Improve Mental Health by Self-Regulation Therapy: A Pilot Study.International journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

David R Pattersona University of Washington School of Medicine , Seattle , USA.
Christine Hoffera University of Washington School of Medicine , Seattle , USA.
Mark P Jensena University of Washington School of Medicine , Seattle , USA.
Shelley A Wiechmana University of Washington School of Medicine , Seattle , USA.
Sam R Sharara University of Washington School of Medicine , Seattle , USA.
Seattle University · USUniversity of Washington · US

Funding

OPTIMIZING THE CONTROL OF PAIN FROM SEVERE BURNSR01GM042725 · NIGMS · UNIVERSITY OF WASHINGTON · PI PATTERSON, DAVID R · 1990 to 2018
$7.5M
Controlling Pain After TraumaR01AR054115 · NIAMS · UNIVERSITY OF WASHINGTON · PI PATTERSON, DAVID R · 2007 to 2017
$4.6M
Identifying Virtual Reality Analgesia Mechanisms by Pharmacologic ManipulationR01DA026438 · NIDA · UNIVERSITY OF WASHINGTON · PI SHARAR, SAM R · 2009 to 2013
$1.9M
NIAMS NIH HHS R01 AR054115NIDA NIH HHS R01 DA026438NIGMS NIH HHS R01 GM042725
6 · The paper itself

Abstract

This pilot study explored the feasibility of using ketamine to increase hypnotizability scores. Ketamine, classified as a dissociative hallucinogen, is used clinically as an anesthetic in high doses and as a treatment for chronic pain and depression in lower doses. Low-dose ketamine can contribute to dissociation and heightened perceptions and feelings of detachment, arguably hypnotic-like states. The authors predicted that a low dose of ketamine in healthy volunteers who scored in the low hypnotizable range on the Stanford Clinical Hypnotizability Scale would (a) cause an increase in subjective ratings of dissociation and (b) lead to an increase in hypnotizability. The findings were in the predicted direction, warranting further investigation into the use of this agent to increase hypnotizability.

Indexed as

AdultAnesthetics, DissociativeDouble-Blind MethodFeasibility StudiesFemaleHumansHypnosisKetamineMaleMiddle AgedPsychological TestsYoung AdultAnesthetics, DissociativeKetamine

Identifiers

PMID29856288
PMCPMC6181123
OpenAlexW2807516377

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.