Evidence map›Paper›PMID 29856264›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2018

Habitual exercise training in older adults offsets the age-related prolongation in leg vasodilator kinetics during single-limb lower body exercise.

William E Hughes, Nicholas T Kruse, Kenichi Ueda, Darren P Casey

Abstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

William E HughesDepartment of Physical Therapy and Rehabilitation Science, Carver College of Medicine, University of Iowa , Iowa City, Iowa.
Nicholas T KruseDepartment of Physical Therapy and Rehabilitation Science, Carver College of Medicine, University of Iowa , Iowa City, Iowa.
Kenichi UedaDepartment of Anesthesia, Carver College of Medicine, University of Iowa , Iowa City, Iowa.
Darren P CaseyDepartment of Physical Therapy and Rehabilitation Science, Carver College of Medicine, University of Iowa , Iowa City, Iowa.

Funding

INTERDISCIPLINARY CARDIOVASCULAR RESEARCH FELLOWSHIPT32HL007121 · NHLBI · UNIVERSITY OF IOWA · PI LONDON, BARRY · 1985 to 2020
$15.1M
NHLBI NIH HHS T32 HL007121
6 · The paper itself

Abstract

We tested the hypothesis that aging is associated with prolonged leg vasodilator kinetics and habitual exercise training in older adults improves these responses relative to untrained older adults. Additionally, we examined the relationship between contraction-induced rapid onset vasodilation (ROV) and vasodilator kinetics. Young ( n = 10), older untrained ( n = 13), and older trained ( n = 14) adults performed single and rhythmic knee-extension contractions at 20% and 40% work-rate maximum (WR

Indexed as

Physical Conditioning, HumanAdultAgedAgingAnaerobic ThresholdBlood PressureExerciseFemaleFemoral ArteryHeart RateHumansKineticsLegLower ExtremityMaleMiddle Agedagingblood flowexercisekineticsvasodilation

Identifiers

PMID29856264
PMCPMC6842877

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.