Evidence map›Paper›PMID 29855627›Full record

ArticleEuropean journal of hybrid imaging2018

Interpreting

Kenneth J Nichols, Brandon Chen, Maria B Tomas, Christopher J Palestro

Abstract read
In one paragraph

Article in European journal of hybrid imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Neuromelanin and TNPJ Parkinson's disease · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kenneth J NicholsDepartment of Radiology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY USA.
Brandon ChenDepartment of Radiology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY USA.
Maria B TomasDepartment of Radiology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY USA.
Christopher J PalestroDepartment of Radiology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDopamine transporter (DaT)

methodsData of 132 consecutive patients undergoing DaT SPECT scans were reviewed retrospectively. The clinical impression in the latest neurology note was utilized as the final clinical diagnosis. Caudate and putamen specific binding ratio (PSBR) were computed.

resultsThirty-four patients (26%) were diagnosed with ET, 85 (64%) with PD, 6 (5%) with multiple system atrophy, and 7 (5%) with DLB. For discriminating DLB from PD, visual analysis was significantly less specific and accurate than the other techniques. However, indexing significantly improved specificity and accuracy of visual scores, such that indexed visual scores were statistically equivalent to all other methods. Indexed PSBR yielded essentially the same results as non-indexed PSBR, for which highest overall test efficacy was achieved.

conclusionsOur results in this small series of patients with DLB suggest that if

Indexed as

123I–ioflupaneBrain SPECTDaTDementia with Lewy bodiesDopamine transportersParkinson’s disease

Identifiers

PMID29855627
PMCPMC5960650

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.