ArticleJournal of musculoskeletal & neuronal interactions2018
Gender-effect on the contractile properties of skeletal muscle in streptozotocin-induced diabetic rats.
Article in Journal of musculoskeletal & neuronal interactions, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 11 citations in OpenAlex.
- Age-related sex differences in tongue strength and muscle morphometry in a rat model.Archives of oral biology · 2023Article
- Mechanisms underlying altered neuromuscular function in people with DPN.European journal of applied physiology · 2023Review
- Universal Recommendations on Planning and Performing the Auditory Brainstem Responses (ABR) with a Focus on Mice and Rats.Audiology research · 2023Article
- Reporting Data on Auditory Brainstem Responses (ABR) in Rats: Recommendations Based on Review of Experimental Protocols and Literature.Brain sciences · 2021Article
- Neuroskeletal Effects of Chronic Bioelectric Nerve Stimulation in Health and Diabetes.Frontiers in neuroscience · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present study, we studied the effect of streptozotocin-induced Type 1 diabetes on contractile properties of soleus muscle in female and young male rats. We hypothesized that the gender affects the contractile function in diabetic rats. Thirty-two Sprague-Dawley rats, male and female, three months old were divided into four groups: Female Non-Diabetic (FND), Female Diabetic (FD), Male Non-Diabetic (MND) and Male Diabetic (MD). Diabetes was induced by a single dose of 60 mg/kg body weight of streptozotocin in citrate buffer pH 4.5 by intraperitoneal route. At 4 weeks after of the dose animals were considered to be diabetic if they had glucose levels ≥20 mmol/L. Soleus muscle mass and twitch force were higher in MND than in FND; in male rats, the diabetes decreased the muscle mass in 34% and the twitch force decayed in 33%; while in diabetic females the muscle mass and twitch force decayed 15% and 10% respectively. Our results showed that the diabetes has gender-dependent effects on the muscle mass and maximal contractile force.
Indexed as
Identifiers
29855448PMC6016489W2989944966What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.