ArticleBMC cancer2018
Risk of second primary Cancer among bladder Cancer patients: a population-based cohort study in Korea.
Article in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
- Second Primary Cancer After Bladder Cancer: A Comprehensive Analysis of a National Cancer Registry.Cancer medicine · 2025Article
- Observational
- Risk of subsequent primary cancers in bladder cancer survivors.Clinical and experimental medicine · 2024Article
- Non-Epstein-Barr Virus Sinonasal Undifferentiated Carcinoma Presenting as Diplopia and Rhinorrhea.Cureus · 2024Article
- Clinical characteristics analysis and prognostic nomogram for predicting survival in patients with second primary prostate cancer: a population study based on SEER database.Journal of cancer research and clinical oncology · 2023Article
- Disparities in cause-specific mortality by race and sex among bladder cancer patients from the SEER database.Cancer causes & control : CCC · 2023Article
- Clinical characteristics and survival of second primary breast carcinoma with extramammary malignancies.Frontiers in oncology · 2023Article
- Article
- Filling the gaps in the research about second primary malignancies after bladder cancer: Focus on race and histology.Frontiers in public health · 2022Article
- Bladder and upper urinary tract cancers as first and second primary cancers.Cancer reports (Hoboken, N.J.) · 2021Article
- Deciphering the Risk of Developing Second Primary Thyroid Cancer Following a Primary Malignancy-Who Is at the Greatest Risk?Cancers · 2021Article
- Lung Metastases Versus Second Primary Lung Cancers in Patients with Primary Urothelial Carcinoma of the Bladder: A National Population-Based Assessment.Bladder cancer (Amsterdam, Netherlands) · 2021Article
- Risk of second primary breast cancer among cancer survivors: Implications for prevention and screening practice.PloS one · 2020Article
- Lung nodules: A comprehensive review on current approach and management.Annals of thoracic medicineReview
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
backgroundFor the expanding population of bladder cancer survivors in Korea, the development of subsequent cancers is a significant concern. Here, we provide the second primary cancer incidence rates and types in Korean patients with bladder cancer.
methodsUsing population-based data from the Korea Central Cancer Registry from 1993 to 2013, we studied the standardized incidence ratios among 48,875 individuals with an initial diagnosis of bladder cancer. Standardized incidence ratios for second primary cancers were evaluated according to age at diagnosis, latency, diagnostic year, and treatment.
resultsOver the same period, the overall risk of a second primary cancer was reduced by 6% in patients with bladder cancer compared with the development of a new malignancy in the general population (standardized incidence ratio = 0.94; 95% CI, 0.91-0.97, p < 0.05). For specific cancers, the standardized incidence ratios for stomach, colon, liver, and non-Hodgkin lymphoma were significantly lower in patients with bladder cancer. However, the risk of prostate and kidney cancer in patients with bladder cancer were significantly increased. The risk of lung squamous cell carcinoma and lung adenocarcinoma as second primary cancers was significantly elevated in patients with bladder cancer.
conclusionKorean patients with bladder cancer have a 6% lower risk of developing a second primary cancer. However, they have a higher risk of developing subsequent prostate and kidney cancers, lung squamous cell carcinoma, and lung adenocarcinoma, suggesting the need for continual intensive cancer surveillance among bladder cancer survivors.
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