Evidence map›Paper›PMID 29855077›Full record

ArticleDiabetic medicine : a journal of the British Diabetic Association2018

Predictors of changing insulin dose requirements and glycaemic control in children, adolescents and young adults with Type 1 diabetes.

G H Teló, C E Dougher, L K Volkening, M L Katz, L M Laffel

Open access · greenAbstract read
In one paragraph

Article in Diabetic medicine : a journal of the British Diabetic Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Type 1 Diabetes Mellitus and Transfer from Pediatric to Adult Care: A Single-Center ExperienceJournal of clinical research in pediatric endocrinology · 2026
    Article
  3. Protective factors in resilient South African youth with type 1 diabetes: A qualitative study.African journal of primary health care & family medicine · 2025
    Article
  4. Article
  5. Article
  6. Barriers to Type 1 Diabetes Adherence in Adolescents.Journal of clinical medicine · 2024
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

G H TelóPediatric, Adolescent and Young Adult Section, Section on Clinical, Behavioral and Outcomes Research, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
C E DougherPediatric, Adolescent and Young Adult Section, Section on Clinical, Behavioral and Outcomes Research, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
L K VolkeningPediatric, Adolescent and Young Adult Section, Section on Clinical, Behavioral and Outcomes Research, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
M L KatzPediatric, Adolescent and Young Adult Section, Section on Clinical, Behavioral and Outcomes Research, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
L M LaffelPediatric, Adolescent and Young Adult Section, Section on Clinical, Behavioral and Outcomes Research, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-2202-492X
Joslin Diabetes Center · US

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI ROHIT N. KULKARNI · 1986 to 2026
$50.5M
TRAINING IN DIABETES AND METABOLISMT32DK007260 · NIDDK · JOSLIN DIABETES CENTER · PI LAURIE J GOODYEAR · 1986 to 2026
$13.6M
CAREER DEVELOPMENT IN DIABETES RESEARCH FOR PEDIATRIC ENDOCRINOLOGISTSK12DK094721 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI LAFFEL, LORI M, WHITE, MORRIS F. · 2011 to 2021
$6.3M
PREVENTING METABOLIC DECLINE IN ADOLESCENTS WITH IDDMR01DK046887 · NIDDK · JOSLIN DIABETES CENTER · PI LAFFEL, LORI M · 1993 to 2001
$515k
Improving Management Strategies for Blood Pressure and Lipids in Pediatric T1DK23HL125976 · NHLBI · JOSLIN DIABETES CENTER · PI KATZ, MICHELLE LYNNE · 2015 to 2017
$514k
CAPES/CNPq 0596-13-2Charles H. Hood FoundationEleanor Chesterman Beatson FundKatherine Adler Astrove Youth Education FundMaria Griffin Drury Pediatric FundNHLBI NIH HHS K23 HL125976NIDDK NIH HHS K12 DK094721NIDDK NIH HHS P30 DK036836NIDDK NIH HHS R01 DK046887NIDDK NIH HHS T32 DK007260NIH HHS K12DK094721NIH HHS K23HL125976NIH HHS P30DK036836NIH HHS R01DK046887NIH HHS T32DK007260
6 · The paper itself

Abstract

aimsTo investigate trajectories of daily insulin dose requirements and glycaemic control in children, adolescents and young adults with Type 1 diabetes and to identify factors associated with changing insulin needs and deterioration in HbA

methodsThe sample was a dynamic cohort of 635 children, adolescents and young adults with Type 1 diabetes from one centre. Data from clinic visits occurring over 20 years (1993-2013) were extracted from medical records. From age 7-24 years, we evaluated HbA

resultsParticipants provided a mean ± sd of 10.7±4.3 years of insulin dose data and 12.0±4.6 years of HbA

conclusionsThis longitudinal assessment identifies clinically meaningful modifiable (e.g. insulin regimen) and non-modifiable (e.g. sex) factors predictive of insulin requirements and HbA

Indexed as

AdolescentAdultBlood GlucoseChildCohort StudiesDiabetes Mellitus, Type 1Dose-Response Relationship, DrugFemaleGlycated HemoglobinHumansInsulinLongitudinal StudiesMalePrognosisYoung AdultBlood GlucoseGlycated HemoglobinInsulin

Identifiers

PMID29855077
PMCPMC6153068
OpenAlexW2806996556

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.